rs6025
|
|
|
0.900 |
GeneticVariation |
BEFREE |
We developed a genome-wide polygenic risk score for venous thromboembolism that identifies 5% of the population at an equivalent incident venous thromboembolism risk to carriers of the established factor V Leiden p.R506Q and prothrombin G20210A mutations.
|
31676865 |
2019 |
rs6025
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Our findings suggest that the risk of VTE by FHMI is not explained by rs8176719 (ABO), rs6025 (F5), rs1799963 (F2), rs2066865 (FGG), and rs2036914 (F11).
|
31124268 |
2019 |
rs6025
|
|
T |
0.900 |
GeneticVariation |
GWASCAT |
We developed a genome-wide polygenic risk score for venous thromboembolism that identifies 5% of the population at an equivalent incident venous thromboembolism risk to carriers of the established factor V Leiden p.R506Q and prothrombin G20210A mutations.
|
31676865 |
2019 |
rs6025
|
|
T |
0.900 |
GeneticVariation |
GWASCAT |
Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism.
|
31420334 |
2019 |
rs6025
|
|
|
0.900 |
GeneticVariation |
BEFREE |
We aimed at establishing a real-time PCR protocol for the detection of the venous thromboembolism associated mutations factor V Leiden (F5 c.1691G>A; p.R506Q) and prothrombin (F2) c.20210G>A from whole blood, without DNA extraction.
|
30439355 |
2019 |
rs6025
|
|
T |
0.900 |
GeneticVariation |
GWASCAT |
Genetic Analysis of Venous Thromboembolism in UK Biobank Identifies the ZFPM2 Locus and Implicates Obesity as a Causal Risk Factor.
|
28373160 |
2017 |
rs6025
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The risk of cancer-related venous thromboembolism was 16.7-fold (95% CI 9.9-28.0) higher in subjects heterozygous for rs6025 compared with non-carriers of this variant without active cancer.
|
27479824 |
2016 |
rs6025
|
|
T |
0.900 |
GeneticVariation |
GWASCAT |
Genome-wide association analysis of self-reported events in 6135 individuals and 252 827 controls identifies 8 loci associated with thrombosis.
|
26908601 |
2016 |
rs6025
|
|
|
0.900 |
GeneticVariation |
BEFREE |
While Factor V Leiden (F5 rs6025 A allele) is a known venous thromboembolism (VTE) risk factor, VTE risk among heterozygous vs. homozygous carriers is uncertain.
|
26970916 |
2016 |
rs6025
|
|
|
0.900 |
GeneticVariation |
BEFREE |
In conclusion, F5 rs6025 and F11 rs2289252 contributed to the risk of recurrent VTE and the combination is of potential clinical relevance for risk prediction.
|
26423325 |
2016 |
rs6025
|
|
T |
0.900 |
GeneticVariation |
GWASCAT |
Meta-analysis of 65,734 individuals identifies TSPAN15 and SLC44A2 as two susceptibility loci for venous thromboembolism.
|
25772935 |
2015 |
rs6025
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Factor V Leiden (FVL or rs6025</span>) and prothrombin gene G20210A (PT or rs1799963) are the genetic variants currently tested for VTE risk assessment.
|
25341889 |
2014 |
rs6025
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Factor V leiden G1691A/R506Q (FVL), prothrombin G20210A (FII) and methylenetetrahydrofolate reductase (MTHFR) C677T are related genetic risk factors for venous thromboembolism.
|
22528331 |
2012 |
rs6025
|
|
T |
0.900 |
GeneticVariation |
GWASDB |
However, F5 was the main signal on 1q24.2 as only ABO SNPs remained significantly associated with VTE after adjusting for F5 rs6025.
|
22672568 |
2012 |
rs6025
|
|
|
0.900 |
GeneticVariation |
BEFREE |
However, F5 was the main signal on 1q24.2 as only ABO SNPs remained significantly associated with VTE after adjusting for F5 rs6025.
|
22672568 |
2012 |
rs6025
|
|
T |
0.900 |
GeneticVariation |
GWASCAT |
However, F5 was the main signal on 1q24.2 as only ABO SNPs remained significantly associated with VTE after adjusting for F5 rs6025.
|
22672568 |
2012 |
rs6025
|
|
|
0.900 |
GeneticVariation |
GWASDB |
Genetics of venous thrombosis: insights from a new genome wide association study.
|
21980494 |
2011 |
rs6025
|
|
|
0.900 |
GeneticVariation |
BEFREE |
A single factor V gene G-A mutation (Arg506Gln) underlying activated protein C (APC) resistance is a common risk factor for venous thromboembolism.
|
9705241 |
1998 |
rs6025
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The risk of recurrent venous thromboembolism in patients with an Arg506-->Gln mutation in the gene for factor V (factor V Leiden).
|
9010145 |
1997 |