Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs751377893
rs751377893
F5
0.100 GeneticVariation BEFREE We aimed at establishing a real-time PCR protocol for the detection of the venous thromboembolism associated mutations factor V Leiden (F5 c.1691G>A; p.R506Q) and prothrombin (F2) c.20210G>A from whole blood, without DNA extraction. 30439355

2019

dbSNP: rs751377893
rs751377893
F5
0.100 GeneticVariation BEFREE In conclusion, coagulant factor V gene G1691A mutation and protein S deficiency constitute important genetic risk factors in patients with VTE in Eastern Algeria. 26304686

2017

dbSNP: rs751377893
rs751377893
F5
0.100 GeneticVariation BEFREE Coagulation factor II G20210A and coagulation factor V (Leiden) G1691A single nucleotide polymorphisms (SNPs) are major inherited risk factors of venous thromboembolism. 22744422

2012

dbSNP: rs751377893
rs751377893
F5
0.100 GeneticVariation BEFREE Factor V leiden G1691A/R506Q (FVL), prothrombin G20210A (FII) and methylenetetrahydrofolate reductase (MTHFR) C677T are related genetic risk factors for venous thromboembolism. 22528331

2012

dbSNP: rs751377893
rs751377893
F5
0.100 GeneticVariation BEFREE Factor V Leiden (Factor V G1691A), prothrombin gene mutation G20210A, and homozygous C677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene are known to predispose venous thromboembolism (VTE). 19520679

2010

dbSNP: rs751377893
rs751377893
F5
0.100 GeneticVariation BEFREE The protein C (PC), protein S, antithrombin activities, homocysteine levels, and factor V Leiden (FVL) G1691A and prothrombin G20210A mutations were evaluated in 191 patients with VTE and 191 controls. 17895505

2008

dbSNP: rs751377893
rs751377893
F5
0.100 GeneticVariation BEFREE Insofar as the inherited prothrombotic single nucleotide polymorphisms (SNPs) factor V G1691A (FV-Leiden), prothrombin (PRT) G20210A, and methylenetetrahydrofolate reductase (MTHFR), C677T are inherited risk factors of venous thromboembolism (VTE), the aim of this study was to determine the prevalence of single and combined SNPs in 198 patients with documented deep venous thrombosis (DVT), and 697 control subjects, and to estimate the associated risks. 16082606

2005

dbSNP: rs751377893
rs751377893
F5
0.100 GeneticVariation BEFREE Factor V G1691A (Leiden), prothrombin G20210A, and methylenetetrahydrofolate reductase (MTHFR) C677T mutations are considered risk factors for venous thromboembolism. 15886665

2005

dbSNP: rs751377893
rs751377893
F5
0.100 GeneticVariation BEFREE Single point mutations in the genes coding for factor V [G1691A; Leiden], prothrombin [PRT; G20210A], and methylenetetrahydrofolate reductase [MTHFR, C677T] were shown to be major inherited predisposing factors for venous thromboembolism. 15353918

2004

dbSNP: rs751377893
rs751377893
F5
0.100 GeneticVariation BEFREE The risk of recurrent venous thromboembolism in carriers and non-carriers of the G1691A allele in the coagulation factor V gene and the G20210A allele in the prothrombin gene. DURAC Trial Study Group. Duration of Anticoagulation. 10365737

1999