|
rs662799
|
|
|
0.070 |
GeneticVariation |
BEFREE |
CAD association was replicated and/or verified for 4 loci: SORT1 rs611917 (p=1.7 × 10(-8)), APOA5 rs662799 (p=0.0014), LDLR rs1433099 (p=2.1 × 10(-7)), and APOE rs7412 (p=6.1 × 10(-13)).
|
23050023 |
2012 |
|
rs1433099
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CAD association was replicated and/or verified for 4 loci: SORT1 rs611917 (p=1.7 × 10(-8)), APOA5 rs662799 (p=0.0014), LDLR rs1433099 (p=2.1 × 10(-7)), and APOE rs7412 (p=6.1 × 10(-13)).
|
23050023 |
2012 |
|
rs7412
|
|
|
0.730 |
GeneticVariation |
BEFREE |
CAD association was replicated and/or verified for 4 loci: SORT1 rs611917 (p=1.7 × 10(-8)), APOA5 rs662799 (p=0.0014), LDLR rs1433099 (p=2.1 × 10(-7)), and APOE rs7412 (p=6.1 × 10(-13)).
|
23050023 |
2012 |
|
rs599839
|
|
|
0.100 |
GeneticVariation |
BEFREE |
CAD association was replicated for three GWAS-identified loci (1p13.3/SORT1 (rs599839), 9p21.3/CDKN2A/2B (rs4977574), and 11q22.3/ PDGFD (rs974819)) in Koreans.
|
23364394 |
2013 |
|
rs4977574
|
|
|
0.890 |
GeneticVariation |
BEFREE |
CAD association was replicated for three GWAS-identified loci (1p13.3/SORT1 (rs599839), 9p21.3/CDKN2A/2B (rs4977574), and 11q22.3/ PDGFD (rs974819)) in Koreans.
|
23364394 |
2013 |
|
rs974819
|
|
|
0.820 |
GeneticVariation |
BEFREE |
CAD association was replicated for three GWAS-identified loci (1p13.3/SORT1 (rs599839), 9p21.3/CDKN2A/2B (rs4977574), and 11q22.3/ PDGFD (rs974819)) in Koreans.
|
23364394 |
2013 |
|
rs10865710
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CAD susceptibility was higher in those with homozygous mutant of rs10865710, rs1805192 and rs4646903 than those with wild-type homozygotes, OR (95%CI) were 1.47 (1.15-1.92), 1.69 (1.27-2.09) and 1.72 (1.35-2.32), respectively.
|
28415751 |
2017 |
|
rs5443
|
|
|
0.040 |
GeneticVariation |
BEFREE |
C825T polymorphism in the G protein beta3 subunit gene (GNB3) has been associated with arterial hypertension, coronary artery disease and myocardial infarction.
|
10704626 |
2000 |
|
rs6020
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Arg485Lys polymorphism of factor V increases the risk of coronary artery disease in a Chinese population.
|
11776127 |
2000 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Glu298-->Asp polymorphism of the eNOS gene appears to be associated with the presence, extent, and severity of angiographically assessed coronary artery disease.
|
12010932 |
2002 |
|
rs16139
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Leucine 7 to proline 7 polymorphism in the preproneuropeptide Y is associated with proteinuria, coronary heart disease, and glycemic control in type 1 diabetic patients.
|
14747236 |
2004 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
C677T mutation of methylenetetrahydrofolate reductase gene and serum homocysteine levels in Turkish patients with coronary artery disease.
|
15648053 |
2006 |
|
rs1801252
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Ser49Gly and haplotype combinations of Ser49Gly and Gly389Arg of the beta(1)AR gene are associated with aerobic power, but not with the response to physical training in patients with CAD included in the CAREGENE study.
|
16421173 |
2006 |
|
rs1199475313
|
|
|
0.010 |
GeneticVariation |
BEFREE |
T64A polymorphism in beta3-adrenergic receptor gene (ADRB3) and coronary heart disease: a case-cohort study and meta-analysis.
|
18088254 |
2008 |
|
rs1320702652
|
|
|
0.010 |
GeneticVariation |
BEFREE |
C34T AMPD1 polymorphism may be associated with reduced frequency of obesity in CAD patients and of hyperglycaemia and diabetes in both CAD and HF patients.
|
18855224 |
2009 |
|
rs2070600
|
|
|
0.100 |
GeneticVariation |
BEFREE |
G82S and -429 T/C polymorphisms of RAGE were associated with the circulating levels of esRAGE but not with CAD in Chinese patients with T2DM.
|
19766904 |
2009 |
|
rs1416580204
|
|
|
0.060 |
GeneticVariation |
BEFREE |
G82S and -429 T/C polymorphisms of RAGE were associated with the circulating levels of esRAGE but not with CAD in Chinese patients with T2DM.
|
19766904 |
2009 |
|
rs7903146
|
|
|
0.030 |
GeneticVariation |
BEFREE |
rs7903146 T allele is associated with diabetes and, in non-diabetic individuals, with a higher prevalence and severity of coronary artery disease and cardiovascular events. name of registry site (see list below), registration number, trial registration URL in brackets.
|
19924244 |
2009 |
|
rs5361
|
|
|
0.080 |
GeneticVariation |
BEFREE |
The interaction of classical risk factors for CAD with S128R polymorphism in our study population showed that the significant determinants of coronary artery disease were presence of diabetes, hypertension, smoking habit, elevated serum triglycerides and low HDL.
|
19942746 |
2009 |
|
rs1458766475
|
|
|
0.070 |
GeneticVariation |
BEFREE |
The interaction of classical risk factors for CAD with S128R polymorphism in our study population showed that the significant determinants of coronary artery disease were presence of diabetes, hypertension, smoking habit, elevated serum triglycerides and low HDL.
|
19942746 |
2009 |
|
rs1799983
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Glu298Asp polymorphism of the endothelial nitric oxide synthase (eNOS) gene (NOS3) has been characterized as a risk factor of hypertension and coronary artery disease.
|
21816783 |
2011 |
|
rs1049353
|
|
|
0.010 |
GeneticVariation |
BEFREE |
G1359A polymorphism of CNR1 may be not associated with T2DM but may contribute to the genetic risk for the presence of CAD in patients with T2DM of Chinese Han population.
|
22138970 |
2012 |
|
rs2943634
|
|
|
0.750 |
GeneticVariation |
BEFREE |
rs2943634 C/A single nucleotide polymorphism (SNP), located in a non coding region of chromosome 2q36.3, has been associated with coronary artery disease in two genome wide association studies.
|
22207032 |
2012 |
|
rs16139
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Leu7Pro polymorphism is associated with the MetS in patients with CAD.
|
22308535 |
2013 |
|
rs3890011
|
|
|
0.030 |
GeneticVariation |
BEFREE |
rs3890011 maybe a novel polymorphism of the CYP4A11 gene associated with CAD in a Han Chinese population.
|
22327816 |
2013 |