| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.770 | GeneticVariation | BEFREE | We genotyped the CAD-associated variants at the LPA (rs10455872) and 9p21 loci (rs1333049) in the GeneCAST (Genetics of Calcific Aortic STenosis) Consortium and conducted a meta-analysis for their association with AVS. | 30482443 | 2019 |
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|
0.770 | GeneticVariation | BEFREE | The genetic variants of rs3135506 (G), rs10455872 (A) and rs3798220 (G) have low frequency in our population and reflected no association with CAD. | 29309886 | 2018 |
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|
G | 0.770 | GeneticVariation | GWASCAT | Association analyses based on false discovery rate implicate new loci for coronary artery disease. | 28714975 | 2017 |
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|
0.770 | GeneticVariation | BEFREE | We confirmed the association of the LPA rs10455872 with CAD in a large sample of Brazilian patients. | 24776095 | 2014 |
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|
0.770 | GeneticVariation | BEFREE | TaqMan SNP genotyping assays were performed to detect the rs6415084, rs3798220 and rs10455872 genotypes in 517 Chinese Han patients with CAD after PCI. | 23978127 | 2013 |
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|
0.770 | GeneticVariation | BEFREE | Individuals with the G allele of rs10455872, which represents approximately one in seven patients, have a higher risk of CAD than the majority of the population even after treatment with statins; and therefore represent a vulnerable group requiring an alternative medication in addition to statin treatment. | 23903772 | 2013 |
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|
0.770 | GeneticVariation | BEFREE | In conclusion, heritable contributions of LPA rs10455872 and rs3798220 to Lp(a) cholesterol levels and to angiographic CAD were prospectively assessed in this study. | 23735648 | 2013 |
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|
0.770 | GeneticVariation | BEFREE | It is unclear whether the LPA variants rs10455872 and rs3798220, which correlate with lipoprotein(a) levels and coronary artery disease (CAD), confer susceptibility predominantly via atherosclerosis or thrombosis. | 22898070 | 2012 |