This meta-analysis suggested that TT genotype in the Arg194Trp polymorphism contributes to the CAD susceptibility, particularly in the Asian population.
Subgroup analysis stratified by control source revealed associations between the Arg1</span>94Trp and Arg399Gln polymorphisms and su</span>sceptibility to CAD</span> under recessive and homozygous modes of inheritance, respectively.
The adjusted risk of having CAD was more evident for rs1799782 (OR = 1.53; 95% CI: 1.16-2.02; P = 0.003), rs1801133 (OR = 1.54; 95% CI: 1.22-1.94; P < 0.001), and rs4846049 (OR = 1.74; 95% CI: 1.13-2.69; P = 0.013) under the recessive model.