rs2036914
|
|
|
0.010 |
GeneticVariation |
BEFREE |
If validated, a F11 rs2036914/FGG rs2066865 risk prediction model should be tested as a stratification tool for prevention of thromboembolism in patients with acute lymphoblastic leukemia.
|
31715544 |
2019 |
rs2043211
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Investigation of NF-κB-94ins/del ATTG and CARD8 (rs2043211) Gene Polymorphism in Acute Lymphoblastic Leukemia.
|
31428046 |
2019 |
rs2066865
|
|
|
0.010 |
GeneticVariation |
BEFREE |
If validated, a F11 rs2036914/FGG rs2066865 risk prediction model should be tested as a stratification tool for prevention of thromboembolism in patients with acute lymphoblastic leukemia.
|
31715544 |
2019 |
rs153109
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of IL-27 rs153109 and rs17855750 Polymorphisms with Risk and Response to Therapy in Acute Lymphoblastic Leukemia.
|
28828696 |
2018 |
rs17855750
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of IL-27 rs153109 and rs17855750 Polymorphisms with Risk and Response to Therapy in Acute Lymphoblastic Leukemia.
|
28828696 |
2018 |
rs231775
|
|
|
0.010 |
GeneticVariation |
BEFREE |
153 donors and 153 children with acute lymphoblastic leukemia, acute myeloid leukemia or juvenile myelomonocytic leukemia who had undergone allogeneic HSCT were genotyped of CTLA-4 gene for rs3087243 (CT60G>A), rs231775 (+ 49 A>G) and rs4553808 using TaqMan real-time polymerase chain reaction.
|
29335768 |
2018 |
rs4553808
|
|
|
0.010 |
GeneticVariation |
BEFREE |
153 donors and 153 children with acute lymphoblastic leukemia, acute myeloid leukemia or juvenile myelomonocytic leukemia who had undergone allogeneic HSCT were genotyped of CTLA-4 gene for rs3087243 (CT60G>A), rs231775 (+ 49 A>G) and rs4553808 using TaqMan real-time polymerase chain reaction.
|
29335768 |
2018 |
rs755622
|
|
|
0.010 |
GeneticVariation |
BEFREE |
MIF-173G/C (rs755622) polymorphism as a risk factor for acute lymphoblastic leukemia development in children.
|
29996006 |
2018 |
rs766639320
|
|
|
0.010 |
GeneticVariation |
BEFREE |
153 donors and 153 children with acute lymphoblastic leukemia, acute myeloid leukemia or juvenile myelomonocytic leukemia who had undergone allogeneic HSCT were genotyped of CTLA-4 gene for rs3087243 (CT60G>A), rs231775 (+ 49 A>G) and rs4553808 using TaqMan real-time polymerase chain reaction.
|
29335768 |
2018 |
rs10740055
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Furthermore, the recessive models revealed that six SNPs were risk factors for acute lymphoblastic leukemia: rs10740055, rs7089424, rs10994982, rs7896246, rs10821938, and rs7923074.
|
28381164 |
2017 |
rs1339159756
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Integration of ruxolitinib into dose-intensified therapy targeted against a novel JAK2 F694L mutation in B-precursor acute lymphoblastic leukemia.
|
27860260 |
2017 |
rs1801265
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The authors conclude that patients carrying the c.85T>C C allele have an increased risk of developing acute lymphoblastic leukemia and have inferior outcome, and that DPYD c.85T>C can be used as a guide for individualized treatment and the decision to utilize 5-fluorouracil in acute lymphoblastic leukemia patients.
|
28618970 |
2017 |
rs2274407
|
|
|
0.010 |
GeneticVariation |
BEFREE |
ABCC4 functional SNP in the 3' splice acceptor site of exon 8 (G912T) is associated with unfavorable clinical outcome in children with acute lymphoblastic leukemia.
|
28550450 |
2017 |
rs4880
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Expression and polymorphism (rs4880) of mitochondrial superoxide dismutase (SOD2) and asparaginase induced hepatotoxicity in adult patients with acute lymphoblastic leukemia.
|
27019981 |
2017 |
rs6479778
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Under the dominant model, SNPs rs7073837, rs10821936, rs7896246, and rs6479778 in males only showed striking association with acute lymphoblastic leukemia.
|
28381164 |
2017 |
rs1057519695
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Early T-Cell Precursor Acute Lymphoblastic Leukemia in an Infant With an NRAS Q61R Mutation and Clinical Features of Juvenile Myelomonocytic Leukemia.
|
27145535 |
2016 |
rs1057519834
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Early T-Cell Precursor Acute Lymphoblastic Leukemia in an Infant With an NRAS Q61R Mutation and Clinical Features of Juvenile Myelomonocytic Leukemia.
|
27145535 |
2016 |
rs11554290
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Early T-Cell Precursor Acute Lymphoblastic Leukemia in an Infant With an NRAS Q61R Mutation and Clinical Features of Juvenile Myelomonocytic Leukemia.
|
27145535 |
2016 |
rs116855232
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In 270 children enrolled in clinical trials for acute lymphoblastic leukemia in Guatemala, Singapore and Japan, we identified four NUDT15 coding variants (p.Arg139Cys, p.Arg139His, p.Val18Ile and p.Val18_Val19insGlyVal) that resulted in 74.4-100% loss of nucleotide diphosphatase activity.
|
26878724 |
2016 |
rs147390019
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In 270 children enrolled in clinical trials for acute lymphoblastic leukemia in Guatemala, Singapore and Japan, we identified four NUDT15 coding variants (p.Arg139Cys, p.Arg139His, p.Val18Ile and p.Val18_Val19insGlyVal) that resulted in 74.4-100% loss of nucleotide diphosphatase activity.
|
26878724 |
2016 |
rs186364861
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In 270 children enrolled in clinical trials for acute lymphoblastic leukemia in Guatemala, Singapore and Japan, we identified four NUDT15 coding variants (p.Arg139Cys, p.Arg139His, p.Val18Ile and p.Val18_Val19insGlyVal) that resulted in 74.4-100% loss of nucleotide diphosphatase activity.
|
26878724 |
2016 |
rs56149945
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated whether an altered individual glucocorticoid sensitivity due to particular glucocorticoid receptor single-nucleotide polymorphisms (SNPs) (N363S, ER22/23EK, and Bcl-1) influences the susceptibility to steroid-related toxicities, prognostic factors, and survival rates in children with acute lymphoblastic leukemia.
|
27050122 |
2016 |
rs121913615
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Retrospective molecular studies detected a MPL W515S homozygous mutation in both the initial and remission marrows for B-ALL, at 30-40% and 80% dosage effect, respectively.
|
25453399 |
2015 |
rs16754
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Wilms tumor gene single nucleotide polymorphism rs16754 predicts a favorable outcome in children with acute lymphoblastic leukemia.
|
26224397 |
2015 |
rs408626
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Influence of dihydrofolate reductase gene polymorphisms rs408626 (-317A>G) and rs442767 (-680C>A) on the outcome of methotrexate-based maintenance therapy in South Indian patients with acute lymphoblastic leukemia.
|
26335211 |
2015 |