Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs17401966
rs17401966
0.900 GeneticVariation BEFREE More well-designed studies with larger sample size and various ethnic groups and risk factors are needed to establish that KIF1B rs17401966 polymorphism is significantly associated with risk of HCC. 30947687

2019

dbSNP: rs17401966
rs17401966
0.900 GeneticVariation BEFREE This meta-analysis suggested that KIF1B (rs17401966) polymorphism could decrease HCC risk in Chinese and in overall population, but not in non-Chinese. 29881295

2018

dbSNP: rs17401966
rs17401966
0.900 GeneticVariation BEFREE The gene-environment interaction between the KIF1B rs17401966 variant and alcohol consumption may contribute to the development of HCC in Chinese individuals. 27122668

2016

dbSNP: rs17401966
rs17401966
0.900 GeneticVariation BEFREE This meta-analysis showed a significant association between KIF1B rs17401966 polymorphism and HCC. 24952890

2014

dbSNP: rs17401966
rs17401966
0.900 GeneticVariation BEFREE A moderate increase in differentiation was noted for rs2596542 (F st = 0.106) and rs17401966 (F st = 0.116), single nucleotide polymorphisms (SNPs) associated with an increased risk of HCC in patients with chronic HCV and HBV, respectively. 24357186

2014

dbSNP: rs17401966
rs17401966
0.900 GeneticVariation BEFREE The SNP rs17401966 was genotyped using the TaqMan allelic discrimination assay in 414 intermediate or advanced hepatocellular carcinoma patients. 25153661

2014

dbSNP: rs17401966
rs17401966
0.900 GeneticVariation BEFREE Homozygous mutation of rs1081432 conferred a 2.68-fold risk of HCC (95% CI 1.35-5.34); however heterozygosity was not statistically significant. rs17401966 heterozygosity or homozygosity was not significantly associated with a increased risk of HCC. 25412941

2014

dbSNP: rs17401966
rs17401966
0.900 GeneticVariation BEFREE Binary logistic regression showed that rs17401966 was not statistically associated with the risk of HCC development in Thai chronic HBV patients (p-value=0.998, OR=1.00 and 95% CI=0.68-1.48). 23803045

2013

dbSNP: rs17401966
rs17401966
0.900 GeneticVariation BEFREE These findings demonstrate that the presence of the G allele at rs17401966 of the KIF1B gene may decrease the risk for HCC and suggest that KIF1B may play a critical role in the development of HCC. 23634229

2013

dbSNP: rs17401966
rs17401966
0.900 GeneticVariation GWASDB Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma. 23242368

2013

dbSNP: rs17401966
rs17401966
0.900 GeneticVariation BEFREE None of the replication cohorts showed associations between rs17401966 and HBV-derived HCC. 22712471

2012

dbSNP: rs17401966
rs17401966
A 0.900 GeneticVariation GWASDB We identified one intronic SNP (rs17401966) in KIF1B on chromosome 1p36.22 that was highly associated with HBV-related HCC and confirmed this association in five additional independent samples, consisting of 1,962 individuals with HCC, 1,430 control subjects and 159 family trios. 20676096

2010

dbSNP: rs17401966
rs17401966
A 0.900 GeneticVariation GWASCAT We identified one intronic SNP (rs17401966) in KIF1B on chromosome 1p36.22 that was highly associated with HBV-related HCC and confirmed this association in five additional independent samples, consisting of 1,962 individuals with HCC, 1,430 control subjects and 159 family trios. 20676096

2010

dbSNP: rs17401966
rs17401966
0.900 GeneticVariation BEFREE We identified one intronic SNP (rs17401966) in KIF1B on chromosome 1p36.22 that was highly associated with HBV-related HCC and confirmed this association in five additional independent samples, consisting of 1,962 individuals with HCC, 1,430 control subjects and 159 family trios. 20676096

2010