rs1799864
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Substitution of V64I in CCR2 relates to delayed progression to AIDS and protects against HIV-1 infection.
|
17504503 |
2007 |
rs1799864
|
|
|
0.070 |
GeneticVariation |
BEFREE |
In addition, we also identified the best three-factor interaction model, including the CCR5 58755-A/G, 59029-A/G, and CCR2-V64I polymorphisms, indicating that there were also strong gene-gene interactions between the CCR5 promoter and CCR2 polymorphisms on the susceptibility of HIV-1 infection.
|
23057571 |
2012 |
rs1799864
|
|
|
0.070 |
GeneticVariation |
BEFREE |
A single nucleotide polymorphism (SNP) at codon 64 in the CC chemokine receptor 2 gene (CCR2 V64I) has been associated with a dominant effect of delaying disease progression from human immunodeficiency virus-1 (HIV-1) infection to acquired immunodeficiency syndrome (AIDS).
|
12325020 |
2002 |
rs1799864
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Here, we determined the association of the CCR5 promoter SNPs, the CCR5-Δ32 mutation, CCR2-V64I SNP, and HH frequencies with resistance/susceptibility to HIV-1 infection in a cohort of HIV-1-serodiscordant couples from Colombia.
|
24098976 |
2013 |
rs1799864
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Four SNPs (CCR2-V64I, CCR5-2459, MIP1A+954, and IL2+3896) and specific haplotypes in the IL2 and CCR2/CCR5 regions were significantly associated with HIV-1 infection susceptibility in different genetic models.
|
16323127 |
2006 |
rs1799864
|
|
|
0.070 |
GeneticVariation |
BEFREE |
No association with CCR2b-V64I (17%) and SDF1-3'A (2%) variants was determined in relation to HIV-1 infection in Gabonese patients.
|
25592723 |
2015 |
rs1799864
|
|
|
0.070 |
GeneticVariation |
BEFREE |
The meta-analysis clarified that the CCR2-Val64Ile polymorphism has no effect on susceptibility to HIV-1 infection in the total population.
|
21461583 |
2011 |
rs8177832
|
|
|
0.040 |
GeneticVariation |
BEFREE |
A meta-analysis of 1624 men with HIV-1 infection and 1523 controls suggested that the association between rs8177832 and susceptibility was not significant.
|
27730383 |
2017 |
rs8177832
|
|
|
0.040 |
GeneticVariation |
BEFREE |
In conclusion, we demonstrated that no genetic H186R polymorphism in exon 4 of APOBEC3G gene is found and therefore neither associated with differential susceptibility to HIV-1 infection/progression among North Indians.
|
18652534 |
2008 |
rs8177832
|
|
|
0.040 |
GeneticVariation |
BEFREE |
This study demonstrates an association of rs6001417, rs8177832, and rs35228531 of APOBEC3G with HIV-1 infection in a population from Burkina Faso.
|
26741797 |
2016 |
rs8177832
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Thus it was concluded that APOBEC3G rs8177832 AA genotype contributes in genetic predisposition to HIV-1 infection in Pakistani population.
|
30338740 |
2018 |
rs763059810
|
|
|
0.030 |
GeneticVariation |
BEFREE |
In addition, we also identified the best three-factor interaction model, including the CCR5 58755-A/G, 59029-A/G, and CCR2-V64I polymorphisms, indicating that there were also strong gene-gene interactions between the CCR5 promoter and CCR2 polymorphisms on the susceptibility of HIV-1 infection.
|
23057571 |
2012 |
rs763059810
|
|
|
0.030 |
GeneticVariation |
BEFREE |
A single nucleotide polymorphism (SNP) at codon 64 in the CC chemokine receptor 2 gene (CCR2 V64I) has been associated with a dominant effect of delaying disease progression from human immunodeficiency virus-1 (HIV-1) infection to acquired immunodeficiency syndrome (AIDS).
|
12325020 |
2002 |
rs763059810
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Structural insight into a novel human CCR5-V130I variant associated with resistance to HIV-1 infection.
|
23869485 |
2014 |
rs10754558
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The 2 polymorphisms rs10754558 in NLRP3 and rs1143634 in IL1B were significantly associated to the HIV-1 infection.
|
22227487 |
2012 |
rs10754558
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The 3'UTR NLRP3 rs10754558 SNP was associated with HIV-1 infection in all the studied groups.
|
20502346 |
2010 |
rs11038628
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Although human TRIM5α (huTRIM5α) does not potently inhibit HIV-1 infection, the ability of huTRIM5α to exhibit some control of HIV-1 infection is evidenced by a single nucleotide polymorphism in huTRIM5α which substitutes aspartic acid to glycine at position 249 (G249D) in the L2 region and is associated with higher susceptibility to HIV-1 infection.
|
30889178 |
2019 |
rs11038628
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We investigated the association between a single nucleotide polymorphism in the TRIM5α linker 2 region (rs11038628), which substituted aspartic acid (D) for glycine (G) at position 249, with susceptibility to HIV-1 infection in Japanese and Indian subjects. rs11038628 is rare in Europeans but common in Asians and Africans.
|
23379364 |
2013 |
rs1544410
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The aim of the present study was to investigate differences in VD₃ mediated effects on rs1544410 genotyped dendritic cells (DCs) and macrophages (MDM), key cells involved in HIV-1 infection.
|
20642435 |
2010 |
rs1544410
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Multilocus logistic regression analysis revealed haplotypes for rs11568820, rs4516035, rs10735810, rs1544410, and rs17878969 polymorphisms showing association with protection to HIV-1 infection (odds ratio, 0.4 [95% confidence interval, 0.22-0.72]; P = .0025), which remained significant after correction for multiple testing.
|
18205531 |
2008 |
rs368234815
|
|
|
0.020 |
GeneticVariation |
BEFREE |
This study aimed to evaluate the association between the IFNL4 rs368234815 (ΔG/TT) dinucleotide polymorphism and the IFN response during chronic HIV-1 infection.
|
27558125 |
2016 |
rs368234815
|
|
|
0.020 |
GeneticVariation |
BEFREE |
IFNL4 rs368234815 polymorphism is associated with innate resistance to HIV-1 infection.
|
26372394 |
2015 |
rs4986790
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Association of toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms with increased infection risk in patients with advanced HIV-1 infection.
|
20521908 |
2010 |
rs4986790
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The TLR4 Asp299Gly heterozygous genotype (OR=2.160; p=0.004) and the mutant allele G (OR=2.051; p=0.002) was higher in HIV-1 infection than healthy controls and also in stage I (OR=2.559; p=0.034) compared to different clinical stages of infection.
|
30569830 |
2019 |
rs10415893
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We tested bone marrow stromal cell antigen 2 (BST-2) gene variants rs3217318, a 19-base-pair insertion/deletion polymorphism in the promoter region, and rs10415893, a tag single-nucleotide polymorphism in the 3' untranslated region, for their association with human immunodeficiency virus type 1 (HIV-1) infection and disease progression.
|
23148293 |
2013 |