Source: CLINVAR ×
Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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T | 0.700 | CausalMutation | CLINVAR | BRCA1 and BRCA2 mutations in women with familial or early-onset breast/ovarian cancer in the Czech Republic. | 15024741 | 2004 |
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T | 0.700 | CausalMutation | CLINVAR | Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing. | 22006311 | 2011 |
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T | 0.700 | CausalMutation | CLINVAR | Haplotype and phenotype analysis of nine recurrent BRCA2 mutations in 111 families: results of an international study. | 9585613 | 1998 |
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T | 0.700 | CausalMutation | CLINVAR | Frequencies of BRCA1 and BRCA2 mutations among 1,342 unselected patients with invasive ovarian cancer. | 21324516 | 2011 |
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T | 0.700 | CausalMutation | CLINVAR | Description and analysis of genetic variants in French hereditary breast and ovarian cancer families recorded in the UMD-BRCA1/BRCA2 databases. | 22144684 | 2012 |
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T | 0.700 | CausalMutation | CLINVAR | Prostate cancer in BRCA2 germline mutation carriers is associated with poorer prognosis. | 20736950 | 2010 |
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T | 0.700 | CausalMutation | CLINVAR | Identification of the breast cancer susceptibility gene BRCA2. | 8524414 | 1996 |
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T | 0.700 | CausalMutation | CLINVAR | Mutations of the BRCA2 gene in ovarian carcinomas. | 8665505 | 1996 |
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T | 0.700 | CausalMutation | CLINVAR | The highly prevalent BRCA2 mutation c.2808_2811del (3036delACAA) is located in a mutational hotspot and has multiple origins. | 23929434 | 2013 |
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T | 0.700 | CausalMutation | CLINVAR | Analysis of BRCA1 and BRCA2 genes in Spanish breast/ovarian cancer patients: a high proportion of mutations unique to Spain and evidence of founder effects. | 12955716 | 2003 |
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T | 0.700 | CausalMutation | CLINVAR | BRCA2 is a moderate penetrance gene contributing to young-onset prostate cancer: implications for genetic testing in prostate cancer patients. | 21952622 | 2011 |
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T | 0.700 | CausalMutation | CLINVAR | De novo recurrent germline mutation of the BRCA2 gene in a patient with early onset breast cancer. | 11158174 | 2001 |