| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
A | 0.700 | CausalMutation | CLINVAR | Multiple gene sequencing for risk assessment in patients with early-onset or familial breast cancer. | 26824983 | 2016 |
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|
A | 0.700 | CausalMutation | CLINVAR | Clinical characteristics of ovarian cancer classified by BRCA1, BRCA2, and RAD51C status. | 24504028 | 2014 |
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|
A | 0.700 | CausalMutation | CLINVAR | An efficient pipeline for the generation and functional analysis of human BRCA2 variants of uncertain significance. | 25146914 | 2014 |
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|
A | 0.700 | CausalMutation | CLINVAR | Development and validation of a new algorithm for the reclassification of genetic variants identified in the BRCA1 and BRCA2 genes. | 25085752 | 2014 |
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|
A | 0.700 | CausalMutation | CLINVAR | A classification model for BRCA2 DNA binding domain missense variants based on homology-directed repair activity. | 23108138 | 2013 |
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|
A | 0.700 | CausalMutation | CLINVAR | BRCA mutation frequency and patterns of treatment response in BRCA mutation-positive women with ovarian cancer: a report from the Australian Ovarian Cancer Study Group. | 22711857 | 2012 |
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|
A | 0.700 | CausalMutation | CLINVAR | Effect of the overexpression of BRCA2 unclassified missense variants on spontaneous homologous recombination in human cells. | 21671020 | 2011 |
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|
A | 0.700 | CausalMutation | CLINVAR | Classifying Variants of Undetermined Significance in BRCA2 with protein likelihood ratios. | 19043619 | 2008 |
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|
A | 0.700 | CausalMutation | CLINVAR | A systematic genetic assessment of 1,433 sequence variants of unknown clinical significance in the BRCA1 and BRCA2 breast cancer-predisposition genes. | 17924331 | 2007 |
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|
A | 0.700 | CausalMutation | CLINVAR | BRCA1 and BRCA2 germline mutation spectrum and frequencies in Belgian breast/ovarian cancer families. | 15026808 | 2004 |