Source: CLINVAR ×
Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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G | 0.700 | CausalMutation | CLINVAR | Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. | 26681312 | 2016 |
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G | 0.700 | CausalMutation | CLINVAR | Frequency of mutations in individuals with breast cancer referred for BRCA1 and BRCA2 testing using next-generation sequencing with a 25-gene panel. | 25186627 | 2015 |
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G | 0.700 | CausalMutation | CLINVAR | The contribution of deleterious germline mutations in BRCA1, BRCA2 and the mismatch repair genes to ovarian cancer in the population. | 24728189 | 2014 |
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A | 0.700 | CausalMutation | CLINVAR | Contribution of BRCA1 and BRCA2 germ-line mutations to the incidence of breast cancer in young women: results from a prospective population-based study in France. | 15887246 | 2005 |
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G | 0.700 | CausalMutation | CLINVAR | Genetic testing in an ethnically diverse cohort of high-risk women: a comparative analysis of BRCA1 and BRCA2 mutations in American families of European and African ancestry. | 16234499 | 2005 |
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|
G | 0.700 | CausalMutation | CLINVAR | BRCA1 and BRCA2 mutations in Scotland and Northern Ireland. | 12698193 | 2003 |
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A | 0.700 | CausalMutation | CLINVAR | Sequence analysis of BRCA1 and BRCA2: correlation of mutations with family history and ovarian cancer risk. | 9667259 | 1998 |