| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
T | 0.700 | CausalMutation | CLINVAR | Germline BRCA mutations are associated with higher risk of nodal involvement, distant metastasis, and poor survival outcomes in prostate cancer. | 23569316 | 2013 |
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T | 0.700 | CausalMutation | CLINVAR | Identifying pancreatic cancer patients for targeted treatment: the challenges and limitations of the current selection process and vision for the future. | 20201734 | 2010 |
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T | 0.700 | CausalMutation | CLINVAR | Prostate cancer in BRCA2 germline mutation carriers is associated with poorer prognosis. | 20736950 | 2010 |
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T | 0.700 | CausalMutation | CLINVAR | Impact of BRCA1 and BRCA2 variants on splicing: clues from an allelic imbalance study. | 19471317 | 2009 |
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|
T | 0.700 | CausalMutation | CLINVAR | BRCA1, BRCA2 and TP53 mutations in very early-onset breast cancer with associated risks to relatives. | 16644204 | 2006 |
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|
T | 0.700 | CausalMutation | CLINVAR | Haplotype and cancer risk analysis of two common mutations, BRCA1 4184del4 and BRCA2 2157delG, in high risk northwest England breast/ovarian families. | 14757871 | 2004 |
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|
T | 0.700 | CausalMutation | CLINVAR | Prediction of pathogenic mutations in patients with early-onset breast cancer by family history. | 12672316 | 2003 |
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|
T | 0.700 | CausalMutation | CLINVAR | 2157delG: a frequent mutation in BRCA2 missed by PTT. | 11106360 | 2000 |
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T | 0.700 | CausalMutation | CLINVAR | Sequence analysis of BRCA1 and BRCA2: correlation of mutations with family history and ovarian cancer risk. | 9667259 | 1998 |
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T | 0.700 | CausalMutation | CLINVAR | Variation of risks of breast and ovarian cancer associated with different germline mutations of the BRCA2 gene. | 8988179 | 1997 |