Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1555600876
rs1555600876
BRCA1 ; NBR2
C 0.700 CausalMutation CLINVAR BRCA1 and BRCA2 germline mutations are frequently demonstrated in both high-risk pancreatic cancer screening and pancreatic cancer cohorts. 24737347

2014
dbSNP: rs1555600876
rs1555600876
BRCA1 ; NBR2
C 0.700 CausalMutation CLINVAR High prevalence of BRCA1 and BRCA2 germline mutations with loss of heterozygosity in a series of resected pancreatic adenocarcinoma and other neoplastic lesions. 23658460

2013
dbSNP: rs1555600876
rs1555600876
BRCA1 ; NBR2
C 0.700 CausalMutation CLINVAR Haplotype analysis of the 185delAG BRCA1 mutation in ethnically diverse populations. 22763381

2013
dbSNP: rs1555600876
rs1555600876
BRCA1 ; NBR2
C 0.700 CausalMutation CLINVAR A high-throughput functional complementation assay for classification of BRCA1 missense variants. 23867111

2013
dbSNP: rs1555600876
rs1555600876
BRCA1 ; NBR2
C 0.700 CausalMutation CLINVAR Nonequivalent gene expression and copy number alterations in high-grade serous ovarian cancers with BRCA1 and BRCA2 mutations. 23633455

2013
dbSNP: rs1555600876
rs1555600876
BRCA1 ; NBR2
C 0.700 CausalMutation CLINVAR Absence of loss of heterozygosity of BRCA1 in a renal tumor from a BRCA1 germline mutation carrier. 23086583

2013
dbSNP: rs1555600876
rs1555600876
BRCA1 ; NBR2
C 0.700 CausalMutation CLINVAR Secondary variants in individuals undergoing exome sequencing: screening of 572 individuals identifies high-penetrance mutations in cancer-susceptibility genes. 22703879

2012
dbSNP: rs1555600876
rs1555600876
BRCA1 ; NBR2
C 0.700 CausalMutation CLINVAR Double heterozygosity for mutations in BRCA1 and BRCA2 in German breast cancer patients: implications on test strategies and clinical management. 22535016

2012
dbSNP: rs1555600876
rs1555600876
BRCA1 ; NBR2
C 0.700 CausalMutation CLINVAR Breast and ovarian cancer risk and risk reduction in Jewish BRCA1/2 mutation carriers. 22430266

2012
dbSNP: rs1555600876
rs1555600876
BRCA1 ; NBR2
C 0.700 CausalMutation CLINVAR Germline BRCA1 mutations increase prostate cancer risk. 22516946

2012
dbSNP: rs1555600876
rs1555600876
BRCA1 ; NBR2
C 0.700 CausalMutation CLINVAR BRCA1/BRCA2 gene mutations/SNPs and BRCA1 haplotypes in early-onset breast cancer patients of Indian ethnicity. 22752604

2012
dbSNP: rs1555600876
rs1555600876
BRCA1 ; NBR2
C 0.700 CausalMutation CLINVAR Predictive factors for BRCA1/BRCA2 mutations in women with ductal carcinoma in situ. 22009639

2012
dbSNP: rs1555600876
rs1555600876
BRCA1 ; NBR2
C 0.700 CausalMutation CLINVAR A 67-year-old woman with BRCA 1 mutation associated with pancreatic adenocarcinoma. 20711688

2011
dbSNP: rs1555600876
rs1555600876
BRCA1 ; NBR2
C 0.700 CausalMutation CLINVAR Prevalence of the most frequent BRCA1 mutations in Polish population. 21503673

2011
dbSNP: rs1555600876
rs1555600876
BRCA1 ; NBR2
C 0.700 CausalMutation CLINVAR Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing. 22006311

2011
dbSNP: rs1555600876
rs1555600876
BRCA1 ; NBR2
C 0.700 CausalMutation CLINVAR BRCA1 185delAG mutant protein, BRAt, up-regulates maspin in ovarian epithelial cells. 19906413

2010
dbSNP: rs1555600876
rs1555600876
BRCA1 ; NBR2
C 0.700 CausalMutation CLINVAR BRCA1 185delAG truncation protein, BRAt, amplifies caspase-mediated apoptosis in ovarian cells. 18594935

2009
dbSNP: rs1555600876
rs1555600876
BRCA1 ; NBR2
C 0.700 CausalMutation CLINVAR Detection of eight BRCA1 mutations in 10 breast/ovarian cancer families, including 1 family with male breast cancer. 7611277

1995