| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
A | 0.700 | CausalMutation | CLINVAR | Patterns and functional implications of rare germline variants across 12 cancer types. | 26689913 | 2015 |
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|
A | 0.700 | CausalMutation | CLINVAR | A review of a multifactorial probability-based model for classification of BRCA1 and BRCA2 variants of uncertain significance (VUS). | 21990134 | 2012 |
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|
A | 0.700 | CausalMutation | CLINVAR | Toward classification of BRCA1 missense variants using a biophysical approach. | 20378548 | 2010 |
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|
A | 0.700 | CausalMutation | CLINVAR | Comprehensive analysis of missense variations in the BRCT domain of BRCA1 by structural and functional assays. | 20516115 | 2010 |
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|
A | 0.700 | CausalMutation | CLINVAR | A systematic genetic assessment of 1,433 sequence variants of unknown clinical significance in the BRCA1 and BRCA2 breast cancer-predisposition genes. | 17924331 | 2007 |
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|
A | 0.700 | CausalMutation | CLINVAR | Classification of BRCA1 missense variants of unknown clinical significance. | 15689452 | 2005 |
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|
A | 0.700 | CausalMutation | CLINVAR | Structure-based assessment of missense mutations in human BRCA1: implications for breast and ovarian cancer predisposition. | 15172985 | 2004 |
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|
A | 0.700 | CausalMutation | CLINVAR | Analysis of missense variation in human BRCA1 in the context of interspecific sequence variation. | 15235020 | 2004 |
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|
A | 0.700 | CausalMutation | CLINVAR | Frequency of germline and somatic BRCA1 mutations in ovarian cancer. | 9796975 | 1998 |
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|
T | 0.700 | CausalMutation | CLINVAR |