rs4994
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Effect of the combination of the variants -75G/A APOA1 and Trp64Arg ADRB3 on the risk of type 2 diabetes (DM2).
|
17727676 |
2008 |
rs1303471186
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genetic testing was positive for DM2 (2650 CCTG repeat) and for a variant c.215C>T (p.Pro72Leu) in the SCN4A gene.
|
25660391 |
2015 |
rs1137100
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, the AA genotype of the K109R LEPR polymorphism was significantly less frequent in centenarians than in the Y, MI, and DM2 groups (p = 0.026, p = 0.013, and p = 0.001, respectively).
|
24549597 |
2014 |
rs1871922
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, the single-nucleotide polymorphism (SNP) rs1871922 located in the first intron of DM2 was genotyped.
|
21224892 |
2011 |
rs622342
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In cancer patients without DM2, this position belonged to AC and AA genotypes of OCT1_rs622342 polymorphism.
|
24145224 |
2013 |
rs4986790
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In conclusion, our results suggest an association between the Asp299Gly polymorphism of the TLR4 gene and early onset of DR in the DM2 patients.
|
19135114 |
2009 |
rs16995309
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, the present data suggest that in a German Caucasian population the Pro387Leu polymorphism of the PTP-1B gene is not associated with DM-2 but may play a role in other metabolic phenotypes.
|
15715684 |
2005 |
rs750359414
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, the present data suggest that in a German Caucasian population the +62G-->A polymorphism of the resistin gene is associated with hypertension but not with DM-2.
|
16313475 |
2005 |
rs1458766475
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the present study, we assessed the possible interactive effect of DM2 and E-selectin S128R polymorphism with respect to its predisposing individuals to CAD, using as a study model a population of 1,112 patients and 427 angiographed controls of Saudi origin.
|
17578587 |
2007 |
rs5361
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the present study, we assessed the possible interactive effect of DM2 and E-selectin S128R polymorphism with respect to its predisposing individuals to CAD, using as a study model a population of 1,112 patients and 427 angiographed controls of Saudi origin.
|
17578587 |
2007 |
rs45539933
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Indeed, several studies have reported that polymorphisms -3826A/G, -1766A/G and -112A/C in the promoter region, Ala64Thr in exon 2 and Met299Leu in exon 5 of UCP1 gene are possibly associated with obesity and/or DM2.
|
22790465 |
2012 |
rs225014
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results indicate that in a case-control study, the homozygosity for D2 Thr92Ala polymorphism is associated with increased risk for DM2.
|
20566590 |
2010 |
rs699
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results suggest that there is an association between the AGT rs699 polymorphism and DM2 in a Brazilian sample.
|
26782563 |
2015 |
rs13266634
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Several investigations in animal models demonstrate the protective role of MT in DM2 and its cardiovascular or renal complications, while a copious literature shows that a common polymorphism (R325W) in ZnT8, which affects the protein's zinc transport activity, is associated with increased DM2 risk.
|
28845600 |
2017 |
rs374057152
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Single nucleotide polymorphism (SNP) C936T of the vascular endothelial growth factor (VEGF) gene and the SNP C242T of the p22phox (CYBA) gene have been investigated in relation to DM2 and its complications.
|
26130419 |
2015 |
rs1800206
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The data suggest that the PPARalpha polymorphism L162V might protect against the development of atherosclerosis or CHD in patients with DM-2.
|
15199365 |
2004 |
rs1466929132
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The pancreatic amyloid main component is a protein known as human islet amyloid polypeptide (hIAPP) or amylin, the most common mutation is the S20G in Asian population with a polymorphic frequency in DM2 Asian patients.
|
16950544 |
2007 |
rs4986790
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Two specific polymorphisms of toll-like receptor 4 (TLR4; Asp299Gly and Thr399Ile) have recently been identified either as candidate protector genes against DM2 and associated neuropathy or risk alleles for the manifestation of diabetic retinopathy.
|
21628510 |
2011 |
rs4986791
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two specific polymorphisms of toll-like receptor 4 (TLR4; Asp299Gly and Thr399Ile) have recently been identified either as candidate protector genes against DM2 and associated neuropathy or risk alleles for the manifestation of diabetic retinopathy.
|
21628510 |
2011 |
rs3025039
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We conclude that the VEGF+936 C/T (rs3025039) gene polymorphisms are related to peripheral neuropathy in Mexican DM2 patients, with the heterozygous genotype potentially conferring a protective effect.
|
31499478 |
2019 |
rs1800562
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We suggest that mutations C282Y and H63D in the HFE gene are not significant risk factors for the development of DM2 in Brazilian women.
|
19876870 |
2009 |
rs1799945
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We suggest that mutations C282Y and H63D in the HFE gene are not significant risk factors for the development of DM2 in Brazilian women.
|
19876870 |
2009 |