Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1800562
rs1800562
0.050 GeneticVariation BEFREE The H63D variant was observed in 35% and the C282Y variant as heterozygous in 5% of patients with MDS with IOL. 25841232

2015

dbSNP: rs1800562
rs1800562
0.050 GeneticVariation BEFREE Increased prevalence of HFE gene mutations is not a generalized feature of MDS, but some subgroups of MDS, especially those characterized by excessive accumulation of ringed sideroblasts, exhibit C282Y mutations at a higher frequency than in other forms of MDS and healthy controls. 17654685

2007

dbSNP: rs1800562
rs1800562
0.050 GeneticVariation BEFREE 49 patients with MM were compared to 61 patients with myelodysplastic syndrome (MDS) concerning the incidence of two genetic variants of the HFE gene (C282Y and H63D) identified with PCR-RFLP. 17001480

2006

dbSNP: rs1800562
rs1800562
0.050 GeneticVariation BEFREE With C282Y, increased OR occurred in non-Hodgkin lymphoma, myeloproliferative disorders, and adenocarcinoma of prostate (2.0, 2.8, and 3.4, respectively); OR was decreased in myelodysplasia (0.4). 15018631

2004

dbSNP: rs1800562
rs1800562
0.050 GeneticVariation BEFREE Genotypic testing of nonselected patients with the myelodysplastic syndrome (MDS) for the C282Y and H63D mutations of the HFE gene responsible for hereditary hemochromatosis revealed a significantly increased frequency of these mutations when compared to healthy blood donors reflecting the average population. 12624489

2003