|
rs121913471
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we presented a heavy pretreated and harbored HER2 V777L mutation de novo stage IV Luminal B (HER2 unamplified) breast cancer patient who achieved an unexpected good response to trastuzumab combined with vinorelbine therapy.
|
31118664 |
2019 |
|
rs63750447
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our study identified, for the first time, that MLH1 V384D germline variant is frequently detected in HER2-positive luminal B</span> BC.
|
31358837 |
2019 |
|
rs16886448
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Through a stratification analysis, <i>5q11.2/MAP3K1</i> (rs16886034, rs16886364, rs16886397, rs1017226, rs16886448) and <i>7q32.3/LINC-PINT</i> (rs4593472) were associated with Luminal A, and <i>10q26.1/FGFR2</i> (rs35054928) was associated with Luminal B.
|
28408616 |
2017 |
|
rs35054928
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Through a stratification analysis, <i>5q11.2/MAP3K1</i> (rs16886034, rs16886364, rs16886397, rs1017226, rs16886448) and <i>7q32.3/LINC-PINT</i> (rs4593472) were associated with Luminal A, and <i>10q26.1/FGFR2</i> (rs35054928) was associated with Luminal B.
|
28408616 |
2017 |
|
rs4593472
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Through a stratification analysis, <i>5q11.2/MAP3K1</i> (rs16886034, rs16886364, rs16886397, rs1017226, rs16886448) and <i>7q32.3/LINC-PINT</i> (rs4593472) were associated with Luminal A, and <i>10q26.1/FGFR2</i> (rs35054928) was associated with Luminal B.
|
28408616 |
2017 |
|
rs1052566
|
|
|
0.010 |
GeneticVariation |
BEFREE |
BRMS1 rs1052566 heterozygous individuals were more likely to have node-positive tumors (OR = 1.58, 95 % CI 1.13-2.23), although there was no dose-response relationship, and those with at least one variant allele were less likely to have the luminal B subtype (AG + AA: OR = 0.59, 95 % CI 0.36-0.98).
|
23771732 |
2013 |
|
rs3116068
|
|
|
0.010 |
GeneticVariation |
BEFREE |
BRMS1 rs3116068 was associated with increased likelihood of having the luminal B and the HER2-enriched tumor subtype (P trend = 0.03).
|
23771732 |
2013 |