|
rs2476601
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The association of PTPN22 rs2476601 with juvenile idiopathic arthritis is specific to females.
|
26291515 |
2015 |
|
rs2476601
|
|
|
0.050 |
GeneticVariation |
BEFREE |
A single nucleotide polymorphism of PTPN22, 1858C>T (rs2476601), disrupts an interaction motif in the protein, and is the most important non-HLA genetic risk factor for rheumatoid arthritis and the second most important for juvenile idiopathic arthritis.
|
25003765 |
2014 |
|
rs2476601
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The association between the functional PTPN22 1858 C/T and MIF -173 C/G polymorphisms and juvenile idiopathic arthritis: a meta-analysis.
|
22327470 |
2012 |
|
rs2476601
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The minor allele of the R620W missense single-nucleotide polymorphism (SNP; rs2476601) in the PTPN22 (protein tyrosine phosphatase non-receptor 22) gene has been reported to be associated with multiple autoimmune diseases, including type 1 diabetes, systemic lupus erythematosus, rheumatoid arthritis, juvenile idiopathic arthritis, autoimmune thyroiditis and vitiligo.
|
16464986 |
2006 |
|
rs2476601
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Association analysis of the 1858C>T polymorphism in the PTPN22 gene in juvenile idiopathic arthritis and other autoimmune diseases.
|
15759012 |
2005 |
|
rs2910164
|
|
|
0.020 |
GeneticVariation |
BEFREE |
These findings did not support the genetic association between miR-146a rs2910164 (G/C) and JRA susceptibility, as well as the association of miR-196a-2 rs11614913 (C/T), miR-146a rs2431697, miR-146a rs57095329, miR-149 rs22928323 with arthritis.
|
31235484 |
2019 |
|
rs7574865
|
|
|
0.020 |
GeneticVariation |
BEFREE |
STAT4 rs7574865 G/T and PTPN22 rs2488457 G/C polymorphisms influence the risk of developing juvenile idiopathic arthritis in Han Chinese patients.
|
25781893 |
2015 |
|
rs7574865
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our meta-analysis revealed that the STAT4 rs7574865 polymorphism is associated with four autoimmune diseases with systemic pathology, including systemic lupus erythematosus (OR = 1.52; 95% CI = 1.48 - 1.56, P<1.0 × 10(-16)), rheumatoid arthritis (OR = 1.27; 95% CI = 1.21 - 1.33, P < 1.00 × 10(-16)), systemic sclerosis (OR = 1.38; 95% CI = 1.27 - 1.50, P < 1.44 × 10(-14)), and primary Sjogren's syndrome (OR = 1.32; 95% CI = 1.01 - 1.73, P = 4.40 × 10(-2)), while no association was found with type I diabetes, juvenile idiopathic arthritis, ulcerative colitis and Crohn's disease.
|
23628400 |
2013 |
|
rs2910164
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our results provide evidence that rs2910164 may play a role in the susceptibility to childhood-onset asthma, but not SLE or JRA in Mexicans.
|
22823586 |
2012 |
|
rs11614913
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These findings did not support the genetic association between miR-146a rs2910164 (G/C) and JRA susceptibility, as well as the association of miR-196a-2 rs11614913 (C/T), miR-146a rs2431697, miR-146a rs57095329, miR-149 rs22928323 with arthritis.
|
31235484 |
2019 |
|
rs2431697
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These findings did not support the genetic association between miR-146a rs2910164 (G/C) and JRA susceptibility, as well as the association of miR-196a-2 rs11614913 (C/T), miR-146a rs2431697, miR-146a rs57095329, miR-149 rs22928323 with arthritis.
|
31235484 |
2019 |
|
rs57095329
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These findings did not support the genetic association between miR-146a rs2910164 (G/C) and JRA susceptibility, as well as the association of miR-196a-2 rs11614913 (C/T), miR-146a rs2431697, miR-146a rs57095329, miR-149 rs22928323 with arthritis.
|
31235484 |
2019 |
|
rs11466018
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We report evolution of PR to juvenile idiopathic arthritis in a Japanese girl with heterozygous complex L110P-E148Q allele of MEFV gene.
|
26457478 |
2018 |
|
rs3743930
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We report evolution of PR to juvenile idiopathic arthritis in a Japanese girl with heterozygous complex L110P-E148Q allele of MEFV gene.
|
26457478 |
2018 |
|
rs2488457
|
|
|
0.010 |
GeneticVariation |
BEFREE |
STAT4 rs7574865 G/T and PTPN22 rs2488457 G/C polymorphisms influence the risk of developing juvenile idiopathic arthritis in Han Chinese patients.
|
25781893 |
2015 |
|
rs361525
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Several meta-analyses and replicated association studies have implicated the minor 'A' variant within the TNF promoter single nucleotide polymorphism (SNP) rs361525 (-238A/G) as a risk allele in joint related disorders, including psoriatic and juvenile idiopathic arthritis, and osteolysis after joint arthroplasty.
|
24069456 |
2013 |