|
rs12979860
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Interleukin 28B rs12979860 genotype and Human Immunodeficiency Virus type 1: Susceptibility, AIDS development and therapeutic outcome.
|
29080719 |
2018 |
|
rs12979860
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Among 632 participants with acute HCV, 35% were female, 82% were Caucasian, 49% had interleukin-28 (IL28)B CC genotype (rs12979860), 96% had injected drugs ever, 47% were infected with HCV genotype 1, and 7% had human immunodeficiency virus (HIV) coinfection.
|
23908124 |
2014 |
|
rs12979860
|
|
|
0.060 |
GeneticVariation |
BEFREE |
In the 286 patients chronically infected by HCV genotypes 1 or 4, both rs14158 CC and rs12979860 CC were associated with a higher rate of sustained virological response (SVR), and these effects were complementary in both HCV-monoinfected and HIV/HCV-coinfected patients.
|
23715768 |
2013 |
|
rs12979860
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The IL28B rs12979860 CC genotype is associated with a higher prevalence of cirrhosis in HIV-HCV-coinfected patients than CT/TT genotypes, suggesting that IL28B CC carriers may experience a more rapid progression of HCV-related liver fibrosis, perhaps as result of increased liver inflammation.
|
21592993 |
2011 |
|
rs12979860
|
|
|
0.060 |
GeneticVariation |
BEFREE |
We aimed to assess the predictive ability of variations in the single-nucleotide polymorphism rs12979860 for SVR in HIV/HCV-coinfected patients, regardless of HCV genotype.
|
20804372 |
2010 |
|
rs12979860
|
|
|
0.060 |
GeneticVariation |
BEFREE |
To assess whether the polymorphism marking the haplotype (rs12979860) also affects other interferon-α responsive chronic viral illnesses, namely hepatitis B virus (HBV) and human immunodeficiency virus (HIV) type 1 infections, we genotyped 226 individuals with HBV persistence, 384 with HBV recovery, and 2548 with or at high risk for HIV infection.
|
20977343 |
2010 |
|
rs1799864
|
|
|
0.040 |
GeneticVariation |
BEFREE |
In a North American, treated, adherent human immunodeficiency virus (HIV)-positive cohort (self-identified whites, n = 175; blacks, n = 218), we investigated whether CYP2B6 (516G>T, 983T>C), UGT2B7 (IVS1+985A>G, 802C>T), MDR1 3435C>T, chemokine (C-C motif) receptor 2 (CCR2) 190G>A, and CCR5 (-2459G>A, Δ32) polymorphisms influenced the time to achieve virologic success (TVLS).
|
21673041 |
2011 |
|
rs1799864
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Both antiretroviral therapy and the human coreceptor polymorphism CCR2-V64I slow progression of human immunodeficiency virus type 1 (HIV-1) disease.
|
15472820 |
2004 |
|
rs1799864
|
|
|
0.040 |
GeneticVariation |
BEFREE |
A single nucleotide polymorphism (SNP) at codon 64 in the CC chemokine receptor 2 gene (CCR2 V64I) has been associated with a dominant effect of delaying disease progression from human immunodeficiency virus-1 (HIV-1) infection to acquired immunodeficiency syndrome (AIDS).
|
12325020 |
2002 |
|
rs1799864
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Of the 99 HIV-seronegative female workers, 19 (19.2%) were heterozygous for the CCR2b-V64I mutation compared with 37 (23%) of the 161 HIV-seropositive FSW (P = 0.47).
|
11468722 |
2001 |
|
rs763059810
|
|
|
0.030 |
GeneticVariation |
BEFREE |
In a North American, treated, adherent human immunodeficiency virus (HIV)-positive cohort (self-identified whites, n = 175; blacks, n = 218), we investigated whether CYP2B6 (516G>T, 983T>C), UGT2B7 (IVS1+985A>G, 802C>T), MDR1 3435C>T, chemokine (C-C motif) receptor 2 (CCR2) 190G>A, and CCR5 (-2459G>A, Δ32) polymorphisms influenced the time to achieve virologic success (TVLS).
|
21673041 |
2011 |
|
rs763059810
|
|
|
0.030 |
GeneticVariation |
BEFREE |
A single nucleotide polymorphism (SNP) at codon 64 in the CC chemokine receptor 2 gene (CCR2 V64I) has been associated with a dominant effect of delaying disease progression from human immunodeficiency virus-1 (HIV-1) infection to acquired immunodeficiency syndrome (AIDS).
|
12325020 |
2002 |
|
rs763059810
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Of the 99 HIV-seronegative female workers, 19 (19.2%) were heterozygous for the CCR2b-V64I mutation compared with 37 (23%) of the 161 HIV-seropositive FSW (P = 0.47).
|
11468722 |
2001 |
|
rs4986790
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The TLR4 (Asp299Gly) SNP is a risk factor in HIV-1 disease susceptibility.
|
30569830 |
2019 |
|
rs4986791
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We hypothesized links between two TLR4 SNPs (rs4986790 leading to Asp299Gly and rs4986791 leading to Thr399Ile) and HIV, to investigate the frequency of TLR4 polymorphism and its role in patients infected with HIV.
|
30569830 |
2019 |
|
rs4149056
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Genotyping was performed on CYP2B6 516G→T, -1459C→T, and -983T→C, ABCB1 3435C→T, and SLCO1B1 521T→C in 229 HIV-infected Chinese pediatric patients (age range 4.0 to 17.5 yrs).
|
28718515 |
2017 |
|
rs1045642
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In a North American, treated, adherent human immunodeficiency virus (HIV)-positive cohort (self-identified whites, n = 175; blacks, n = 218), we investigated whether CYP2B6 (516G>T, 983T>C), UGT2B7 (IVS1+985A>G, 802C>T), MDR1 3435C>T, chemokine (C-C motif) receptor 2 (CCR2) 190G>A, and CCR5 (-2459G>A, Δ32) polymorphisms influenced the time to achieve virologic success (TVLS).
|
21673041 |
2011 |
|
rs4149056
|
|
|
0.020 |
GeneticVariation |
BEFREE |
* A single nucleotide polymorphism (SNP) in the SLCO1B1 gene (521T-->C) was associated with plasma levels of lopinavir in HIV-infected individuals.
|
20078617 |
2010 |
|
rs4986790
|
|
|
0.020 |
GeneticVariation |
BEFREE |
This study suggests an association between the presence of TLR4 Asp299Gly and Thr399Ile polymorphisms and the occurrence of serious infections in HIV-1 infected patients with a history of nadir CD4 cell count of <100 cells/mm(3).
|
20521908 |
2010 |
|
rs4986791
|
|
|
0.020 |
GeneticVariation |
BEFREE |
This study suggests an association between the presence of TLR4 Asp299Gly and Thr399Ile polymorphisms and the occurrence of serious infections in HIV-1 infected patients with a history of nadir CD4 cell count of <100 cells/mm(3).
|
20521908 |
2010 |
|
rs1045642
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The 3435C-->T polymorphism at the multidrug resistance gene 1 (MDR1) was examined in 74 patients with human immunodeficiency virus who initiated atazanavir therapy.
|
16355344 |
2006 |
|
rs2910164
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Pregnant women ( n = 300) were subdivided into low, medium and high NOx exposure groups, genotyped for the miRNA-146a G/C rs2910164 using polymerase chain reaction-restriction fragment length polymorphism, and further stratified based on HIV status.
|
29896975 |
2019 |
|
rs738409
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Human immunodeficiency virus (HIV)-induced metabolic abnormalities and antiretroviral therapy (ART), genetic factors, most importantly the rs738409 C > G p.I148M variant in the patatin-like phospholipase domain containing 3 (PNPLA3)-gene, as well as hepatitis C virus (HCV) coinfection may all cause hepatic steatosis (HS).
|
31067123 |
2019 |
|
rs12252
|
|
|
0.010 |
GeneticVariation |
BEFREE |
By performing high-throughput RNA sequencing on primary dendritic cells and peripheral blood mononuclear cells isolated from pandemic H1N1 influenza and human immunodeficiency virus-1 (HIV-1) infected patients we show that full-length IFITM3 mRNA is dominantly expressed (>99%) across all rs12252 genotypes.
|
29202190 |
2018 |
|
rs1188975135
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we show that the S61P mutation in human A3C (A3C.S61P) boosted hypermutation in the viral genomes of simian immunodeficiency virus Δvif and murine leukemia virus but not in human immunodeficiency virus HIV-1Δvif.
|
28315663 |
2017 |