|
rs113488022
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Patients with BRAF (v-Raf murine sarcoma viral oncogene homolog B) V600E-mutated metastatic colorectal cancer (mCRC) have a poor prognosis.
|
30662270 |
2019 |
|
rs113488022
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Activating BRAF (V-raf murine sarcoma viral oncogene homolog B) mutations occur in approximately 5% to 10% of patients with metastatic colorectal cancer, mostly V600E mutation, and it is associated with distinct clinical and pathological features.
|
27341594 |
2017 |
|
rs113488022
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Approximately 2% of lung adenocarcinomas have BRAF (v-Raf murine sarcoma viral oncogene homolog B) mutations, including V600E and other types.
|
26200454 |
2015 |
|
rs113488022
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Histiocytic sarcoma exhibited the highest rate of BRAF(V600E) (62.5%, five of eight), followed by Langerhans cell tumours (25%, seven of 28), FDC sarcoma (18.5%, five of 27) and giant cell tumour (6.7%, two of 30).
|
24720374 |
2014 |
|
rs113488022
|
|
|
0.080 |
GeneticVariation |
BEFREE |
BRAF (v-raf murine sarcoma viral oncogene homologue B) V600E mutations have been detected with high frequency in melanocytic naevi.
|
25039578 |
2014 |
|
rs113488022
|
|
|
0.080 |
GeneticVariation |
BEFREE |
One melanoma-sarcoma pair showed identical BRAF V600E mutations.
|
24117833 |
2014 |
|
rs113488022
|
|
|
0.080 |
GeneticVariation |
BEFREE |
To explore the mutation frequencies of BRAF(V600E) (V-raf murine sarcoma virus oncogene homolog B1) and NRAS (neuroblastoma ras viral oncogene homolog) codon 61 in CMNs of Chinese, we selected 55 paraffin-embedded tissue blocks, including 37 cases of medium CMNs (1.5-20cm) and 18 cases of giant CMNs (>20 cm).
|
21430505 |
2011 |
|
rs113488022
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Frequent somatic mutations of BRAF (v-raf murine sarcoma viral oncogene homolog B) exon T1799A, which are implicated in the initial events of promutagenic cellular proliferation, are detected in both malignant melanomas (MM) and melanocytic nevi (MN).
|
21326296 |
2011 |