|
rs121913322
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
|
rs121964872
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
|
rs80357522
|
|
CT |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs80357678
|
|
C |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs864622149
|
|
T |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs28897696
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Any one of four germ-line mutations in the C-terminal region found in patients with breast or ovarian cancer (Ala-1708-->Glu, Gln-1756 C+, Met-1775-->Arg, Tyr-1853 ->Stop), had markedly impaired transcription activity.
|
8942979 |
1996 |
|
rs2227564
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In order to elucidate the possible role of the Pro121Leu exchange in uPA and the Ala/Thr variants in the signal sequence of PAI-1 in the development and/or progression of human ovarian cancer, we studied the presence of these mutants or variants in a series of 22 ovarian cancer tissues.
|
9194591 |
1997 |
|
rs1463038513
|
|
|
0.020 |
GeneticVariation |
BEFREE |
To determine whether the excess of colon cancer in some breast-ovarian cancer families is related to the I1307K mutation, we evaluated 264 Ashkenazi Jews from 158 families.
|
9407954 |
1997 |
|
rs1801155
|
|
|
0.020 |
GeneticVariation |
BEFREE |
To determine whether the excess of colon cancer in some breast-ovarian cancer families is related to the I1307K mutation, we evaluated 264 Ashkenazi Jews from 158 families.
|
9407954 |
1997 |
|
rs397516436
|
|
|
0.010 |
GeneticVariation |
BEFREE |
High prevalence of codon 213Arg-->Stop mutations of the TP53 gene in human ovarian cancer in the southwestern part of The Netherlands.
|
9579562 |
1998 |
|
rs1463038513
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In the Ashkenazi Jewish population, the I1307K allele is unlikely to increase the risk of ovarian cancer or of cancer in general.
|
9679945 |
1998 |
|
rs1801155
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In the Ashkenazi Jewish population, the I1307K allele is unlikely to increase the risk of ovarian cancer or of cancer in general.
|
9679945 |
1998 |
|
rs2070074
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Our results support previous reports of an association of impaired galactose metabolism with serous and undifferentiated ovarian cancers but contradict previous findings of increased N314D mutation frequencies among women with endometriosis and endometrioid and clear cell sub-types ovarian cancer.
|
9714048 |
1998 |
|
rs1799950
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The rare form of the Q356R polymorphism was significantly ( P = 0.03) associated with a family history of ovarian cancer, suggesting that this polymorphism may influence ovarian cancer risk.
|
10196379 |
1999 |
|
rs80357796
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The rare form of the Q356R polymorphism was significantly ( P = 0.03) associated with a family history of ovarian cancer, suggesting that this polymorphism may influence ovarian cancer risk.
|
10196379 |
1999 |
|
rs2070074
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The difference was most evident for endometrioid and clear cell types of ovarian cancer, in which 3.9% of cases were found to be homozygous for N314D compared with 0.4% of controls, yielding an odds ratio and 95% confidence interval of 14.17 (2.62-76.60).
|
10667469 |
2000 |
|
rs1051740
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The microsomal epoxide hydrolase Tyr113His polymorphism: association with risk of ovarian cancer.
|
11255266 |
2001 |
|
rs1042838
|
|
|
0.030 |
GeneticVariation |
BEFREE |
No significant association between progesterone receptor exon 4 Val660Leu G/T polymorphism and risk of ovarian cancer.
|
11323389 |
2001 |
|
rs1456079929
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To assess whether the progesterone receptor (PR) exon 4 valine to leucine amino acid variant is associated with specific tumour characteristics or with overall risk of ovarian cancer, we examined 551 cases of epithelial ovarian cancer and 298 unaffected controls for the underlying G-->T nucleotide substitution polymorphism.
|
11323389 |
2001 |
|
rs2070074
|
|
|
0.050 |
GeneticVariation |
BEFREE |
We found no effect of N314D GALT genotype on the risk of borderline ovarian cancer (odds ratio (OR)=0.91; 95% confidence interval (CI)=0.54-1.6) or invasive ovarian cancer (OR=0.78; 95% CI= 0.53-1.2).
|
11936817 |
2002 |
|
rs1799983
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated two polymorphisms (exon 7 Glu298Asp and a 27-bp repeat in intron 4) of the gene encoding endothelial nitric oxide synthase (Nos3) in 130 patients with ovarian cancer, 26 patients with borderline ovarian cancer, and 133 healthy age-matched Caucasian women using PCR and pyrosequencing, respectively.
|
12144818 |
2002 |
|
rs2070074
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Association of galactose-1-phosphate uridyltransferase activity and N314D genotype with the risk of ovarian cancer.
|
12370157 |
2002 |
|
rs2070074
|
|
|
0.050 |
GeneticVariation |
BEFREE |
We conclude that the GALT N314D allele does not predispose to epithelial ovarian cancer.
|
12869412 |
2003 |
|
rs144848
|
|
|
0.040 |
GeneticVariation |
BEFREE |
There was no association between BRCA2 N372H and risk of borderline or invasive epithelial ovarian cancer.
|
14555511 |
2003 |
|
rs748876625
|
|
|
0.020 |
GeneticVariation |
BEFREE |
A group of 63 families from the Pomerania-Kujawy region were analyzed for three BRCA1 gene Polish founder mutations, 5382insC, 300T>G, and 4153delA, because of breast (BrCa) and/or ovarian cancer (OvCa) history.
|
14986830 |
2003 |