DisGeNET - a database of gene-disease associations

Malignant neoplasm of colon and/or rectum, C4722085

Variant: rs1056836 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs1056836

CYP1B1

0.030

GeneticVariation

BEFREE

The previous published data on the association between CYP1A2*F (rs762551), CYP1B1 Leu432Val (rs1056836), Asn453Ser (rs180040), and Arg48Gly (rs10012) polymorphisms and colorectal cancer risk remained controversial.

25115775

2014

dbSNP:

rs1056836

CYP1B1

0.030

GeneticVariation

BEFREE

CYP1B1 Leu432Val polymorphism and colorectal cancer risk among Caucasians: a meta-analysis.

22190224

2012

dbSNP:

rs1056836

CYP1B1

0.030

GeneticVariation

BEFREE

Haplotypes of rs1056827 and rs10012 or rs1056827 and rs1056836 revealed an association with colorectal cancer which was significantly stronger in the homozygous carriers.

20701755

2010