Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.100 | GeneticVariation | BEFREE | Association of XRCC1 Arg399Gln Polymorphism with Colorectal Cancer Risk: A HuGE Meta Analysis of 35 Studies. | 25921133 | 2015 |
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0.100 | GeneticVariation | BEFREE | XRCC1 R399Q polymorphism and colorectal cancer risk in the Chinese Han population: a meta-analysis. | 25582318 | 2015 |
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0.100 | GeneticVariation | BEFREE | The relationships between the X-ray repair cross-complementing 1 (XRCC1) Arg399Gln polymorphism (rs25487, G > A) and responses to platinum-based chemotherapy of gastric and colorectal cancer patients are controversial. | 24224851 | 2014 |
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0.100 | GeneticVariation | BEFREE | The XRCC1 Arg399Gln gene polymorphism and risk of colorectal cancer: a study in Kashmir. | 24377605 | 2013 |
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0.100 | GeneticVariation | BEFREE | These results indicate that XRCC1 Arg399Gln polymorphism is associated with response to oxaliplantin-based chemotherapy and TTP in advanced colorectal cancer in Chinese population. | 23327191 | 2013 |
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0.100 | GeneticVariation | BEFREE | Our meta-analysis provides an evidence for the association between XRCC1 Arg399Gln polymorphism and colorectal cancer</span> risk in Chinese population, and XRCC1 Arg399Gln variant genotypes contribute to increased risk of colorectal cancer in Chinese. | 23712778 | 2013 |
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0.100 | GeneticVariation | BEFREE | X-ray repair cross-complementing group 1 Arg399Gln gene polymorphism and susceptibility to colorectal cancer:a meta-analysis. | 23188703 | 2013 |
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0.100 | GeneticVariation | BEFREE | Association between polymorphisms of XRCC1 Arg399Gln and XPD Lys751Gln genes and prognosis of colorectal cancer in a Chinese population. | 23317245 | 2012 |
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0.100 | GeneticVariation | BEFREE | The results suggest that XRCC1 Arg399Gln polymorphisms is associated with the response to oxaliplatin-based chemotherapy and time to progression in advanced colorectal cancer in Chinese population. | 22549274 | 2012 |
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0.100 | GeneticVariation | BEFREE | No association of XRCC1 polymorphisms Arg194Trp and Arg399Gln with colorectal cancer risk. | 21612998 | 2011 |
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0.100 | GeneticVariation | BEFREE | Our results showed no evidence of a relationship between the XRCC1 Arg194Trp and Arg399Gln polymorphisms and the risk of lung and colorectal cancer. | 19031937 | 2009 |
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0.100 | GeneticVariation | BEFREE | However, the distributions of OGG1 Ser326Cys and XRCC1 Arg399Gln were not associated with a colorectal cancer risk. | 18823566 | 2008 |
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0.100 | GeneticVariation | BEFREE | Our results suggest that the XRCC1 Arg399Gln polymorphism may contribute to the risk of early-onset colorectal cancer and the XRCC3 Thr241Met polymorphism may modify the risk for meat-associated colorectal cancer. | 15914278 | 2005 |
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0.100 | GeneticVariation | BEFREE | This study was designed to examine the polymorphisms associated with three DNA repair genes, namely: XRCC1 Arg399Gln, XRCC3 Thr241Met and XPD Lys751Gln, and investigate their role as susceptibility markers for colorectal cancer. | 15679883 | 2005 |
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0.100 | GeneticVariation | BEFREE | We performed a case-control study (51 cases and 100 controls) to test the association between two polymorphisms: Arg399Gln in the XRCC1 gene and Thr241Met in the XRCC3 gene and colorectal cancer risk. | 15354414 | 2004 |