Disease: Psoriasis
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs4986790
TLR4
0.438 0.800 9 117713024 missense variant A/G;T snv 6.1E-02; 4.0E-06 223
rs2910164
MIR3142HG ; MIR146A
0.447 0.880 5 160485411 mature miRNA variant C/G snv 0.71; 4.1E-06 0.70 193
rs1800629
TNF
0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14 169
rs2476601
AP4B1-AS1 ; PTPN22
0.498 0.800 1 113834946 missense variant A/G snv 0.93 0.93 121
rs2275913
IL17A
0.514 0.760 6 52186235 upstream gene variant G/A snv 0.28 105
rs763780
IL17F
0.531 0.720 6 52236941 missense variant T/C snv 6.7E-02 6.6E-02 87
rs3212227
IL12B
0.566 0.840 5 159315942 3 prime UTR variant T/G snv 0.26 65
rs361525
TNF
0.562 0.760 6 31575324 upstream gene variant G/A snv 4.6E-02 62
rs2066844
NOD2
0.587 0.520 16 50712015 missense variant C/T snv 2.6E-02 2.9E-02 54
rs20541
IL13 ; TH2LCRR
0.585 0.720 5 132660272 missense variant A/G snv 0.72 0.77 52
rs11209026
IL23R
0.597 0.680 1 67240275 missense variant G/A snv 4.2E-02 4.6E-02 46
rs2066845
NOD2
0.611 0.600 16 50722629 missense variant G/C;T snv 1.1E-02; 2.2E-04 46
rs1800925
IL13 ; TH2LCRR
0.627 0.560 5 132657117 non coding transcript exon variant C/G;T snv 37
rs34536443
TYK2
0.667 0.400 19 10352442 missense variant G/C snv 2.7E-02 2.8E-02 25
rs2201841
C1orf141 ; IL23R
0.716 0.440 1 67228519 intron variant A/G;T snv 14
rs30187
ERAP1
0.732 0.360 5 96788627 missense variant T/A;C snv 0.62 14
rs33980500
TRAF3IP2-AS1 ; TRAF3IP2
0.742 0.200 6 111592059 missense variant C/T snv 8.6E-02 9.7E-02 14
rs6887695 0.732 0.440 5 159395637 intron variant G/C snv 0.35 14
rs7530511
IL23R ; C1orf141
0.742 0.400 1 67219704 missense variant T/A;C snv 0.88 12
rs2066808
STAT2
0.807 0.280 12 56344189 intron variant A/G snv 0.21 8
rs848
IL13 ; TH2LCRR
0.807 0.240 5 132660808 3 prime UTR variant A/C snv 0.67 8
rs12191877
HLA-B
0.851 0.120 6 31285148 intron variant C/T snv 0.12 7
rs281875214
CARD14
0.790 0.160 17 80183976 missense variant A/C snv 7
rs12188300 0.807 0.120 5 159402519 intron variant A/G;T snv 6
rs281875215
CARD14
0.807 0.160 17 80182790 missense variant G/A snv 8.0E-06 6