Disease: Multiple Sclerosis
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs1217691063
MTHFR
0.330 0.920 1 11796309 missense variant A/G snv 4.0E-06 7.0E-06 614
rs397507444
MTHFR
0.405 0.880 1 11794407 missense variant T/G snv 306
rs6265
BDNF ; BDNF-AS
0.436 0.760 11 27658369 missense variant C/T snv 0.19 0.15 272
rs4680
COMT ; MIR4761
0.442 0.920 22 19963748 missense variant G/A snv 0.46 0.44 249
rs759834365
BDNF-AS ; BDNF
0.448 0.760 11 27658456 missense variant C/T snv 1.2E-05 237
rs1801133
MTHFR
0.472 0.880 1 11796321 missense variant G/A snv 0.31 0.27 174
rs662
PON1
0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42 157
rs1805087
MTR
0.496 0.800 1 236885200 missense variant A/G snv 0.20 0.21 135
rs699
AGT
0.501 0.800 1 230710048 missense variant A/G snv 0.55 0.58 134
rs854560
PON1
0.513 0.800 7 95316772 missense variant A/C;G;N;T snv 0.29 113
rs1267969615
ACE
0.532 0.760 17 63490960 missense variant T/C snv 4.0E-06 100
rs1801131
MTHFR
0.535 0.840 1 11794419 missense variant T/G snv 0.29 0.26 93
rs1049353
CNR1
0.630 0.600 6 88143916 synonymous variant C/T snv 0.21 0.20 42
rs746682028
BDNF ; BDNF-AS
0.645 0.480 11 27658414 missense variant C/A;T snv 4.0E-06; 4.0E-06 36
rs1445081098
COMT ; MIR4761
0.724 0.480 22 19963746 missense variant G/C snv 4.0E-06 17
rs6994992
NRG1
0.790 0.120 8 31638065 upstream gene variant C/A;T snv 13
rs6971
TSPO
0.742 0.200 22 43162920 missense variant A/G snv 0.76 0.75 11
rs779867
GRM7
0.776 0.120 3 7442784 intron variant T/C;G snv 9
rs4774388
RORA
0.807 0.200 15 61174799 intron variant C/T snv 0.81 6
rs1064395
NCAN
0.882 0.120 19 19250926 3 prime UTR variant G/A snv 0.24 3