Disease: Impaired cognition
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs1217691063
MTHFR
0.330 0.920 1 11796309 missense variant A/G snv 4.0E-06 7.0E-06 614
rs6265
BDNF ; BDNF-AS
0.436 0.760 11 27658369 missense variant C/T snv 0.19 0.15 272
rs4680
COMT ; MIR4761
0.442 0.920 22 19963748 missense variant G/A snv 0.46 0.44 249
rs1799983
NOS3
0.430 0.880 7 150999023 missense variant T/A;G snv 0.75 246
rs759834365
BDNF-AS ; BDNF
0.448 0.760 11 27658456 missense variant C/T snv 1.2E-05 237
rs1801133
MTHFR
0.472 0.880 1 11796321 missense variant G/A snv 0.31 0.27 174
rs1805087
MTR
0.496 0.800 1 236885200 missense variant A/G snv 0.20 0.21 135
rs1801131
MTHFR
0.535 0.840 1 11794419 missense variant T/G snv 0.29 0.26 93
rs2236225
MTHFD1
0.614 0.640 14 64442127 missense variant G/A snv 0.44 0.38 52
rs6295
HTR1A
0.645 0.200 5 63962738 intron variant C/G snv 0.49 40
rs746682028
BDNF ; BDNF-AS
0.645 0.480 11 27658414 missense variant C/A;T snv 4.0E-06; 4.0E-06 36
rs1006737
CACNA1C
0.695 0.120 12 2236129 intron variant G/A snv 0.36 27
rs165599
ARVCF ; COMT
0.677 0.280 22 19969258 3 prime UTR variant G/A snv 0.56 27
rs1344706
ZNF804A
0.701 0.160 2 184913701 intron variant A/C;T snv 21
rs1611115
DBH
0.732 0.280 9 133635393 upstream gene variant T/C snv 0.80 16
rs1625579
MIR137HG
0.763 0.160 1 98037378 intron variant G/T snv 0.78 14
rs12273363
BDNF
0.807 0.120 11 27723312 intron variant T/C snv 0.16 11
rs1108580
DBH
0.790 0.240 9 133639992 splice region variant A/G snv 0.45 0.54 9
rs17518584
CADM2
0.827 0.160 3 85555773 intron variant C/T snv 0.50 8
rs6584400
NRG3
0.851 0.120 10 81896770 intron variant G/A snv 0.22 6
rs1938526
ANK3
0.882 0.040 10 60540625 intron variant A/G snv 8.3E-02 3
rs4354668
SLC1A2
0.882 0.040 11 35419429 5 prime UTR variant T/G snv 0.54 3