Disease: Non-Small Cell Lung Carcinoma
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs762846821
TP53
0.614 0.320 17 7675151 missense variant C/A;T snv 8.0E-06 57
rs2279744
MDM2
0.605 0.640 12 68808800 intron variant T/G snv 0.31 48
rs397517132
EGFR
0.623 0.280 7 55191846 missense variant A/T snv 48
rs121913273
PIK3CA
0.605 0.440 3 179218294 missense variant G/A;C snv 44
rs121913355
BRAF
0.641 0.520 7 140781602 missense variant C/A;G;T snv 4.0E-06 42
rs727503094
LRRC56 ; HRAS
0.633 0.440 11 534287 missense variant GC/AG;AT;TA;TT mnv 41
rs10741657
CYP2R1
0.637 0.520 11 14893332 upstream gene variant A/G snv 0.65 34
rs1800449
LOX
0.641 0.400 5 122077513 missense variant C/A;T snv 4.0E-06; 0.17 33
rs112445441
KRAS
0.658 0.400 12 25245347 missense variant C/A;G;T snv 32
rs10505477
CASC8 ; PCAT1 ; POU5F1B
0.658 0.400 8 127395198 intron variant A/G snv 0.40 31
rs121913227
BRAF
0.653 0.320 7 140753336 missense variant AC/CT;TT mnv 31
rs752021744
PIK3CB
0.689 0.440 3 138759306 missense variant T/C snv 1.2E-05 29
rs876658657
MLH1
0.677 0.280 3 37020356 missense variant A/G snv 4.0E-06 25
rs3219489
MUTYH
0.672 0.360 1 45331833 missense variant C/A;G snv 0.29 0.27 24
rs187115
CD44
0.695 0.320 11 35154612 intron variant T/C snv 0.37 22
rs744166
STAT3
0.689 0.560 17 42362183 intron variant A/G snv 0.48 22
rs9651118
MTHFR
0.683 0.480 1 11802157 intron variant T/C snv 0.18 20
rs6068816
CYP24A1
0.752 0.200 20 54164552 synonymous variant C/T snv 0.12 8.9E-02 12
rs1950902
MTHFD1
0.776 0.240 14 64415662 missense variant A/G snv 0.83 0.83 11
rs28929495
EGFR
0.807 0.120 7 55174014 missense variant G/A;C;T snv 9
rs909797662
EGFR
0.790 0.120 7 55191837 missense variant G/A snv 8
rs1051753269
EGFR
0.790 0.120 7 55174029 missense variant G/A snv 7.0E-06 7
rs8073069
BIRC5
0.807 0.200 17 78213692 upstream gene variant G/C snv 0.33 7