Disease: Neoplasm Metastasis
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs121913530
KRAS
0.583 0.640 12 25245351 missense variant C/A;G;T snv 63
rs11554290
NRAS
0.583 0.600 1 114713908 missense variant T/A;C;G snv 59
rs351855
FGFR4
0.597 0.560 5 177093242 missense variant G/A snv 0.33 0.26 58
rs762846821
TP53
0.614 0.320 17 7675151 missense variant C/A;T snv 8.0E-06 57
rs11549465
HIF1A-AS3 ; HIF1A
0.597 0.680 14 61740839 missense variant C/T snv 8.8E-02 7.7E-02 55
rs121434592
AKT1
0.595 0.640 14 104780214 missense variant C/T snv 4.0E-06 54
rs758272654
GNAS
0.611 0.680 20 58909201 synonymous variant T/C snv 4.0E-06 7.0E-06 50
rs2736098
TERT
0.600 0.600 5 1293971 synonymous variant C/T snv 0.29 0.22 48
rs397517132
EGFR
0.623 0.280 7 55191846 missense variant A/T snv 48
rs895819
MIR23A ; LOC284454 ; MIR27A ; MIR24-2
0.623 0.560 19 13836478 non coding transcript exon variant T/A;C;G snv 0.34 0.38 46
rs3212986
CD3EAP ; ERCC1
0.620 0.400 19 45409478 stop gained C/A;G;T snv 0.29; 4.3E-06; 4.3E-06 42
rs1057519975
TP53
0.649 0.480 17 7675209 missense variant A/C;G;T snv 34
rs121913364
BRAF
0.641 0.520 7 140753334 missense variant T/C;G snv 4.0E-06 34
rs112445441
KRAS
0.658 0.400 12 25245347 missense variant C/A;G;T snv 32
rs121913227
BRAF
0.653 0.320 7 140753336 missense variant AC/CT;TT mnv 31
rs17577
SLC12A5-AS1 ; MMP9
0.649 0.520 20 46014472 missense variant G/A;C snv 0.16 31
rs2227983
EGFR
0.658 0.520 7 55161562 missense variant G/A;C;T snv 0.29 31
rs11549467
HIF1A ; HIF1A-AS3
0.653 0.400 14 61740857 missense variant G/A snv 8.9E-03 7.0E-03 30
rs61764370
KRAS
0.662 0.320 12 25207290 3 prime UTR variant A/C snv 6.2E-02 29
rs752021744
PIK3CB
0.689 0.440 3 138759306 missense variant T/C snv 1.2E-05 29
rs1870377
KDR
0.695 0.520 4 55106807 missense variant T/A snv 0.22 0.20 25
rs121913444
EGFR
0.724 0.160 7 55191831 missense variant T/A;C;G snv 18
rs4244285
CYP2C19
0.695 0.360 10 94781859 synonymous variant G/A;C snv 0.18 18
rs767649
MIR155HG ; MIR155
0.695 0.480 21 25572410 intron variant T/A snv 7.5E-02 18
rs1800372
TP53
0.752 0.240 17 7674892 synonymous variant T/A;C snv 1.3E-02 15