Disease: Major Depressive Disorder
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs1217691063
MTHFR
0.330 0.920 1 11796309 missense variant A/G snv 4.0E-06 7.0E-06 614
rs397507444
MTHFR
0.405 0.880 1 11794407 missense variant T/G snv 306
rs4680
COMT ; MIR4761
0.442 0.920 22 19963748 missense variant G/A snv 0.46 0.44 249
rs1799983
NOS3
0.430 0.880 7 150999023 missense variant T/A;G snv 0.75 246
rs1045642
ABCB1
0.456 0.840 7 87509329 synonymous variant A/G;T snv 0.50 214
rs1801133
MTHFR
0.472 0.880 1 11796321 missense variant G/A snv 0.31 0.27 174
rs662
PON1
0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42 157
rs1805087
MTR
0.496 0.800 1 236885200 missense variant A/G snv 0.20 0.21 135
rs2228570
VDR
0.521 0.760 12 47879112 start lost A/C;G;T snv 0.63 99
rs9939609
FTO
0.559 0.720 16 53786615 intron variant T/A snv 0.41 98
rs2032582
ABCB1
0.538 0.800 7 87531302 missense variant A/C;T snv 0.54; 3.8E-02 97
rs16944
IL1B
0.531 0.920 2 112837290 upstream gene variant A/G snv 0.57 92
rs25531
SLC6A4 ; LOC105371720
0.581 0.520 17 30237328 upstream gene variant T/C snv 0.18 72
rs4994
ADRB3
0.578 0.640 8 37966280 missense variant A/G snv 0.11 9.2E-02 65
rs1128503
ABCB1
0.564 0.760 7 87550285 synonymous variant A/G snv 0.54 0.63 64
rs1143634
IL1B
0.597 0.680 2 112832813 synonymous variant G/A snv 0.19 0.19 52
rs1799883
FABP2
0.658 0.440 4 119320747 missense variant T/A;C;G snv 0.73 36
rs4986938
ESR2
0.641 0.600 14 64233098 3 prime UTR variant C/T snv 0.31 0.33 35
rs10936599
MYNN
0.637 0.600 3 169774313 synonymous variant C/T snv 0.29 0.21 32
rs1256049
ESR2
0.645 0.560 14 64257333 synonymous variant C/T snv 6.7E-02 6.3E-02 32
rs174537
TMEM258 ; MYRF
0.708 0.400 11 61785208 non coding transcript exon variant G/T snv 0.28 23
rs334558
LOC107986119 ; GSK3B
0.701 0.320 3 120094435 upstream gene variant A/G snv 0.51 20
rs3749474
TMEM165 ; CLOCK
0.724 0.320 4 55434518 3 prime UTR variant C/T snv 0.33 17
rs2470890
CYP1A2
0.742 0.320 15 74755085 synonymous variant T/C snv 0.57 12
rs6438552
GSK3B
0.790 0.280 3 119912967 intron variant A/G snv 0.54 9