Disease: Metabolic Syndrome X
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs8192678
PPARGC1A
0.667 0.440 4 23814039 missense variant C/T snv 0.31 0.26 28
rs3135506
APOA5
0.708 0.400 11 116791691 missense variant G/A;C snv 3.0E-05; 6.8E-02 26
rs1041981
LOC100287329 ; LTA
0.667 0.520 6 31573007 missense variant C/A snv 0.35 0.38 25
rs76863441
PLA2G7
0.672 0.440 6 46709361 missense variant C/A snv 4.5E-03 1.3E-03 25
rs660339
UCP2
0.695 0.320 11 73978059 missense variant G/A snv 0.41 0.43 24
rs708272
CETP
0.708 0.440 16 56962376 intron variant G/A snv 0.42 0.38 24
rs2383207
CDKN2B-AS1
0.695 0.280 9 22115960 intron variant A/G snv 0.64 22
rs1051931
PLA2G7
0.708 0.400 6 46705206 missense variant A/G snv 0.81 0.79 19
rs328
LPL
0.732 0.440 8 19962213 stop gained C/G snv 9.2E-02 9.0E-02 19
rs16147
LOC107986777 ; NPY
0.695 0.400 7 24283791 upstream gene variant T/C snv 0.48 18
rs1800775
CETP
0.790 0.240 16 56961324 upstream gene variant C/A;G snv 0.51; 5.7E-06 18
rs3091244
CRP
0.724 0.280 1 159714875 upstream gene variant G/A;T snv 17
rs116843064
ANGPTL4
0.776 0.160 19 8364439 missense variant G/A snv 1.3E-02 1.5E-02 16
rs2295490
TRIB3
0.724 0.320 20 388261 missense variant A/G;T snv 0.18; 4.0E-06 16
rs11066001
BRAP
0.763 0.360 12 111681367 intron variant T/C snv 5.8E-03 15
rs2943634 0.763 0.200 2 226203364 intergenic variant A/C;G snv 15
rs80356814
LMNA
0.732 0.320 1 156138697 synonymous variant C/T snv 8.0E-06 15
rs2516839
USF1
0.732 0.320 1 161043331 5 prime UTR variant C/T snv 0.49 14
rs9282541
ABCA1
0.790 0.160 9 104858554 missense variant G/A snv 1.3E-02 4.4E-03 13
rs1761667
CD36
0.752 0.320 7 80615623 intron variant G/A snv 0.49 12
rs1320702652
MFAP1
0.752 0.160 15 43824536 missense variant G/A snv 4.0E-06 11
rs185847354
ADIPOQ ; ADIPOQ-AS1
0.763 0.160 3 186854460 missense variant T/C snv 3.1E-04 7.0E-05 11
rs2000813
LIPG
0.763 0.200 18 49567494 missense variant C/A;T snv 4.0E-06; 0.27; 4.0E-06 0.23 9
rs3732581
PARL
0.790 0.120 3 183840614 missense variant C/G;T snv 0.46; 1.2E-05 9
rs1049673
CD36
0.807 0.160 7 80677034 3 prime UTR variant C/G;T snv 7