Disease: Impaired cognition
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs1006737
CACNA1C
0.695 0.120 12 2236129 intron variant G/A snv 0.36 27
rs33939927
LRRK2
0.708 0.120 12 40310434 missense variant C/A;G;T snv 4.0E-06; 1.2E-05 24
rs2072446
LOC100288866 ; MIR6165 ; NGFR
0.776 0.160 17 49510457 missense variant C/T snv 5.2E-02 4.1E-02 11
rs1805054
HTR6
0.708 0.200 1 19666020 synonymous variant C/T snv 0.15; 8.0E-06 0.16 17
rs6295
HTR1A
0.645 0.200 5 63962738 intron variant C/G snv 0.49 40
rs63750424
MAPT
0.677 0.240 17 46024061 missense variant C/T snv 1.6E-05 30
rs63751273
MAPT
0.645 0.280 17 46010389 missense variant C/T snv 42
rs53576
OXTR ; CAV3
0.641 0.320 3 8762685 intron variant A/G;T snv 42
rs5522
NR3C2
0.732 0.320 4 148436323 missense variant C/T snv 0.88 0.89 19
rs74315401
PRNP
0.683 0.320 20 4699525 missense variant C/T snv 32
rs2075650
TOMM40
0.662 0.360 19 44892362 intron variant A/G snv 0.13 0.13 45
rs1800497
ANKK1
0.620 0.400 11 113400106 missense variant G/A snv 0.26 0.26 56
rs421016
GBA
0.683 0.440 1 155235252 missense variant A/C;G snv 8.0E-06; 1.3E-03 30
rs34637584
LRRK2
0.583 0.480 12 40340400 missense variant G/A snv 5.3E-04 3.6E-04 78
rs1229984
ADH1B
0.570 0.560 4 99318162 missense variant T/C;G snv 0.90 83
rs1232898090
PPARA
0.637 0.600 22 46198429 missense variant G/C;T snv 4.0E-06; 4.0E-06 40
rs9340799
ESR1
0.583 0.680 6 151842246 intron variant A/G snv 0.32 62
rs9939609
FTO
0.559 0.720 16 53786615 intron variant T/A snv 0.41 98
rs6265
BDNF ; BDNF-AS
0.436 0.760 11 27658369 missense variant C/T snv 0.19 0.15 272
rs759834365
BDNF-AS ; BDNF
0.448 0.760 11 27658456 missense variant C/T snv 1.2E-05 237
rs1805087
MTR
0.496 0.800 1 236885200 missense variant A/G snv 0.20 0.21 135
rs1800795
IL6-AS1 ; IL6 ; STEAP1B
0.494 0.840 7 22727026 intron variant C/G snv 0.71 140
rs1801282
PPARG
0.500 0.840 3 12351626 missense variant C/G snv 0.11 8.9E-02 131
rs1805192
PPARG
0.510 0.840 3 12379739 missense variant C/G snv 121
rs1799983
NOS3
0.430 0.880 7 150999023 missense variant T/A;G snv 0.75 246