Disease: Polycystic Ovary Syndrome
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs2059806
INSR
0.807 0.240 19 7166365 synonymous variant C/G;T snv 4.0E-06; 0.26 7
rs316019
SLC22A2
0.790 0.360 6 160249250 missense variant A/C snv 0.90 0.89 8
rs2241767
ADIPOQ-AS1 ; ADIPOQ
0.763 0.440 3 186853407 intron variant A/G snv 0.10 10
rs290487
TCF7L2
0.776 0.280 10 113149972 intron variant C/T snv 0.16 10
rs17300539
ADIPOQ
0.752 0.320 3 186841671 upstream gene variant G/A snv 5.3E-02 11
rs3736228
LRP5
0.752 0.400 11 68433827 missense variant C/T snv 0.13 0.11 13
rs2295490
TRIB3
0.724 0.320 20 388261 missense variant A/G;T snv 0.18; 4.0E-06 16
rs8192678
PPARGC1A
0.667 0.440 4 23814039 missense variant C/T snv 0.31 0.26 28
rs696217
GHRL ; GHRLOS
0.662 0.640 3 10289773 missense variant G/T snv 8.8E-02 7.1E-02 32
rs833061
VEGFA
0.605 0.600 6 43769749 upstream gene variant C/G;T snv 42
rs4420638
APOC1
0.708 0.520 19 44919689 downstream gene variant A/G snv 0.18 43
rs1799964
LTA ; LOC100287329 ; TNF
0.608 0.760 6 31574531 upstream gene variant T/C snv 0.19 47
rs2241766
ADIPOQ ; ADIPOQ-AS1
0.608 0.720 3 186853103 synonymous variant T/C;G snv 8.0E-06; 0.13 48
rs1501299
ADIPOQ ; ADIPOQ-AS1
0.597 0.720 3 186853334 intron variant G/C;T snv 52
rs7903146
TCF7L2
0.554 0.680 10 112998590 intron variant C/G;T snv 93
rs5498
ICAM4 ; ICAM1
0.531 0.760 19 10285007 missense variant A/G snv 0.44 0.37 99
rs5443
CDCA3 ; GNB3
0.532 0.760 12 6845711 synonymous variant C/T snv 0.36 0.44 106
rs1800470
TGFB1
0.515 0.840 19 41353016 missense variant G/A;C snv 0.55; 2.4E-04 107
rs854560
PON1
0.513 0.800 7 95316772 missense variant A/C;G;N;T snv 0.29 113
rs1805192
PPARG
0.510 0.840 3 12379739 missense variant C/G snv 121
rs1801282
PPARG
0.500 0.840 3 12351626 missense variant C/G snv 0.11 8.9E-02 131
rs4880
SOD2
0.500 0.840 6 159692840 missense variant A/G snv 0.48 0.47 131
rs699
AGT
0.501 0.800 1 230710048 missense variant A/G snv 0.55 0.58 134
rs1800795
IL6-AS1 ; IL6 ; STEAP1B
0.494 0.840 7 22727026 intron variant C/G snv 0.71 140
rs662
PON1
0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42 157