Disease: Metabolic Syndrome X
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs1800206
PPARA
0.641 0.640 22 46218377 missense variant C/G snv 4.3E-02 4.2E-02 35
rs763351020
SERPINE1
0.633 0.560 7 101132046 missense variant C/T snv 4.0E-06 35
rs8192678
PPARGC1A
0.667 0.440 4 23814039 missense variant C/T snv 0.31 0.26 28
rs5219
KCNJ11
0.701 0.360 11 17388025 stop gained T/A;C snv 0.64 25
rs660339
UCP2
0.695 0.320 11 73978059 missense variant G/A snv 0.41 0.43 24
rs17611
C5
0.732 0.480 9 121006922 missense variant C/T snv 0.47 0.36 14
rs2230774
ROCK2
0.807 0.240 2 11218994 missense variant G/C;T snv 0.49 12
rs6921438 0.776 0.360 6 43957870 intergenic variant G/A;C snv 10
rs2000813
LIPG
0.763 0.200 18 49567494 missense variant C/A;T snv 4.0E-06; 0.27; 4.0E-06 0.23 9
rs1800592 0.807 0.200 4 140572807 upstream gene variant T/C snv 0.40 8
rs10738760 0.807 0.320 9 2691186 regulatory region variant A/G snv 0.56 7
rs1549758
NOS3
0.807 0.360 7 150998638 synonymous variant T/C snv 0.76 0.76 7
rs1799768
SERPINE1
0.807 0.360 7 101126425 upstream gene variant -/A;C ins 6
rs3818569
RXRG
0.925 0.160 1 165419892 synonymous variant G/A snv 2