Disease: Ischemic stroke
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs1217691063
MTHFR
0.330 0.920 1 11796309 missense variant A/G snv 4.0E-06 7.0E-06 614
rs1799983
NOS3
0.430 0.880 7 150999023 missense variant T/A;G snv 0.75 246
rs1799945
LOC108783645 ; HFE
0.452 0.760 6 26090951 missense variant C/G;T snv 0.11 0.10 226
rs1801133
MTHFR
0.472 0.880 1 11796321 missense variant G/A snv 0.31 0.27 174
rs699
AGT
0.501 0.800 1 230710048 missense variant A/G snv 0.55 0.58 134
rs4880
SOD2
0.500 0.840 6 159692840 missense variant A/G snv 0.48 0.47 131
rs5443
CDCA3 ; GNB3
0.532 0.760 12 6845711 synonymous variant C/T snv 0.36 0.44 106
rs1137101
LEPR
0.554 0.760 1 65592830 missense variant A/G snv 0.51 0.50 77
rs2234693
ESR1
0.555 0.680 6 151842200 intron variant T/C snv 0.47 77
rs429358
APOE
0.590 0.600 19 44908684 missense variant T/C snv 0.14 0.16 66
rs11591147
PCSK9
0.677 0.360 1 55039974 missense variant G/A;T snv 1.2E-02 28
rs76863441
PLA2G7
0.672 0.440 6 46709361 missense variant C/A snv 4.5E-03 1.3E-03 25
rs693
APOB
0.708 0.440 2 21009323 synonymous variant G/A snv 0.39 0.38 24
rs505151
PCSK9
0.732 0.360 1 55063514 missense variant G/A snv 0.95 0.90 18
rs17321515 0.776 0.200 8 125474167 intron variant A/G snv 0.49 16
rs137929307
LDLR
0.752 0.240 19 11116928 missense variant G/A snv 4.4E-05 4.9E-05 12
rs28942084
LDLR
0.763 0.200 19 11120436 missense variant C/A;T snv 2.8E-05 4.2E-05 11
rs5888
SCARB1
0.752 0.200 12 124800202 synonymous variant A/G;T snv 0.59; 4.0E-06 11
rs6782181
MRAS
0.851 0.160 3 138386212 intron variant G/A;C snv 6