Disease: Obesity
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs7903146
TCF7L2
0.554 0.680 10 112998590 intron variant C/G;T snv 93
rs2070600
AGER
0.561 0.760 6 32183666 missense variant C/T snv 5.3E-02 3.6E-02 82
rs731236
VDR
0.542 0.760 12 47844974 synonymous variant A/G snv 0.33 0.34 81
rs1800796
IL6-AS1 ; STEAP1B ; IL6
0.555 0.760 7 22726627 non coding transcript exon variant G/C snv 9.9E-02 74
rs7041
GC
0.576 0.800 4 71752617 missense variant A/C;T snv 0.52; 4.0E-06 64
rs361525
TNF
0.562 0.760 6 31575324 upstream gene variant G/A snv 4.6E-02 62
rs1800566
NQO1
0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21 59
rs2228145
IL6R
0.602 0.720 1 154454494 missense variant A/C;T snv 0.38; 1.2E-05 57
rs758272654
GNAS
0.611 0.680 20 58909201 synonymous variant T/C snv 4.0E-06 7.0E-06 50
rs243865
MMP2
0.600 0.640 16 55477894 intron variant C/T snv 0.19 48
rs1799724
LTA ; TNF
0.600 0.680 6 31574705 upstream gene variant C/T snv 8.5E-02 47
rs895819
MIR23A ; LOC284454 ; MIR27A ; MIR24-2
0.623 0.560 19 13836478 non coding transcript exon variant T/A;C;G snv 0.34 0.38 46
rs266729
ADIPOQ
0.637 0.560 3 186841685 upstream gene variant C/A;G;T snv 37
rs9282861
SULT1A1
0.658 0.440 16 28606193 missense variant C/T snv 31
rs1042028
SULT1A1
0.658 0.440 16 28606193 missense variant C/T snv 0.22 0.30 30
rs1143623
IL1B
0.677 0.440 2 112838252 upstream gene variant C/G snv 0.24 29
rs12255372
TCF7L2
0.667 0.480 10 113049143 intron variant G/A;T snv 28
rs8193036
IL17A
0.689 0.600 6 52185695 upstream gene variant C/T snv 0.72 21
rs3819024
IL17A
0.701 0.560 6 52185988 upstream gene variant A/G snv 0.34 17