Disease: Metabolic Syndrome X
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs6265
BDNF ; BDNF-AS
0.436 0.760 11 27658369 missense variant C/T snv 0.19 0.15 272
rs759834365
BDNF-AS ; BDNF
0.448 0.760 11 27658456 missense variant C/T snv 1.2E-05 237
rs1801282
PPARG
0.500 0.840 3 12351626 missense variant C/G snv 0.11 8.9E-02 131
rs1805192
PPARG
0.510 0.840 3 12379739 missense variant C/G snv 121
rs9939609
FTO
0.559 0.720 16 53786615 intron variant T/A snv 0.41 98
rs738409
PNPLA3
0.557 0.720 22 43928847 missense variant C/G snv 0.28 0.22 88
rs4994
ADRB3
0.578 0.640 8 37966280 missense variant A/G snv 0.11 9.2E-02 65
rs324420
FAAH
0.637 0.440 1 46405089 missense variant C/A snv 0.24 0.26 48
rs3856806
PPARG
0.637 0.440 3 12434058 synonymous variant C/T snv 0.13 0.11 41
rs1799883
FABP2
0.658 0.440 4 119320747 missense variant T/A;C;G snv 0.73 36
rs660339
UCP2
0.695 0.320 11 73978059 missense variant G/A snv 0.41 0.43 24
rs2229616
MC4R
0.732 0.200 18 60372043 missense variant C/T snv 1.6E-02 1.6E-02 22
rs4148325
UGT1A8 ; UGT1A5 ; UGT1A10 ; UGT1A7 ; UGT1A1 ; UGT1A9 ; UGT1A3 ; UGT1A4 ; UGT1A6
0.851 0.080 2 233764663 intron variant C/T snv 0.36 11
rs7566605
LOC107985940
0.752 0.320 2 118078449 regulatory region variant C/G snv 0.70 11