Disease: Pain
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs1217691063
MTHFR
0.330 0.920 1 11796309 missense variant A/G snv 4.0E-06 7.0E-06 614
rs6265
BDNF ; BDNF-AS
0.436 0.760 11 27658369 missense variant C/T snv 0.19 0.15 272
rs4680
COMT ; MIR4761
0.442 0.920 22 19963748 missense variant G/A snv 0.46 0.44 249
rs759834365
BDNF-AS ; BDNF
0.448 0.760 11 27658456 missense variant C/T snv 1.2E-05 237
rs1045642
ABCB1
0.456 0.840 7 87509329 synonymous variant A/G;T snv 0.50 214
rs11614913
HOXC6 ; MIR196A2
0.512 0.760 12 53991815 mature miRNA variant C/T snv 0.39 0.34 111
rs1801394
FASTKD3 ; MTRR
0.531 0.840 5 7870860 missense variant A/G snv 0.47 0.45 101
rs2032582
ABCB1
0.538 0.800 7 87531302 missense variant A/C;T snv 0.54; 3.8E-02 97
rs6313
HTR2A
0.562 0.640 13 46895805 synonymous variant G/A snv 0.41 0.40 82
rs731236
VDR
0.542 0.760 12 47844974 synonymous variant A/G snv 0.33 0.34 81
rs17576
MMP9
0.557 0.760 20 46011586 missense variant A/G snv 0.39 0.36 73
rs9340799
ESR1
0.583 0.680 6 151842246 intron variant A/G snv 0.32 62
rs6280
DRD3
0.602 0.520 3 114171968 missense variant C/T snv 0.63 0.54 57
rs6277
DRD2
0.689 0.480 11 113412737 synonymous variant G/A snv 0.41 0.38 36
rs4818
COMT ; MIR4761
0.683 0.440 22 19963684 synonymous variant C/G;T snv 0.34 27
rs4633
COMT ; MIR4761
0.695 0.400 22 19962712 synonymous variant C/T snv 0.46 0.45 25
rs893924483
BDNF ; BDNF-AS
0.716 0.280 11 27658285 missense variant C/A;T snv 4.0E-06 1.4E-05 23
rs1044396
CHRNA4
0.742 0.240 20 63349782 missense variant G/A;C snv 0.47; 6.1E-05 17
rs6746030
SCN1A-AS1 ; SCN9A
0.763 0.320 2 166242648 missense variant A/G snv 0.88 0.88 16
rs885479
MC1R
0.732 0.280 16 89919746 missense variant G/A snv 0.15 8.3E-02 16
rs6269
COMT ; MIR4761
0.827 0.240 22 19962429 5 prime UTR variant A/G snv 0.38 10
rs6267
MIR4761 ; COMT
0.827 0.200 22 19962740 missense variant G/A;T snv 4.8E-05; 1.4E-02 9
rs1044397
CHRNA4
0.851 0.160 20 63349752 synonymous variant C/T snv 0.48 0.41 7
rs2295633
FAAH
0.827 0.120 1 46408711 intron variant A/G;T snv 7
rs324419
FAAH
0.925 0.120 1 46406314 stop gained T/A;C snv 0.87 3