Disease: Metabolic Syndrome X
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs1217691063
MTHFR
0.330 0.920 1 11796309 missense variant A/G snv 4.0E-06 7.0E-06 614
rs397507444
MTHFR
0.405 0.880 1 11794407 missense variant T/G snv 306
rs6265
BDNF ; BDNF-AS
0.436 0.760 11 27658369 missense variant C/T snv 0.19 0.15 272
rs759834365
BDNF-AS ; BDNF
0.448 0.760 11 27658456 missense variant C/T snv 1.2E-05 237
rs662
PON1
0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42 157
rs5443
CDCA3 ; GNB3
0.532 0.760 12 6845711 synonymous variant C/T snv 0.36 0.44 106
rs2234693
ESR1
0.555 0.680 6 151842200 intron variant T/C snv 0.47 77
rs9340799
ESR1
0.583 0.680 6 151842246 intron variant A/G snv 0.32 62
rs324420
FAAH
0.637 0.440 1 46405089 missense variant C/A snv 0.24 0.26 48
rs1800587
IL1A
0.620 0.720 2 112785383 upstream gene variant G/A;C snv 0.32 43
rs1049353
CNR1
0.630 0.600 6 88143916 synonymous variant C/T snv 0.21 0.20 42
rs16139
NPY ; LOC107986777
0.658 0.560 7 24285260 missense variant T/A;C snv 4.0E-06; 3.0E-02 36
rs1535255
CNR1
0.807 0.120 6 88151489 intron variant T/G snv 0.21 8
rs7973260
KSR2
0.851 0.120 12 117937681 intron variant A/G snv 0.83 7
rs2199503
GSK3B
0.851 0.080 3 120059642 intron variant T/C snv 0.79 4