Disease: Diabetic Nephropathy
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs1217691063
MTHFR
0.330 0.920 1 11796309 missense variant A/G snv 4.0E-06 7.0E-06 614
rs397507444
MTHFR
0.405 0.880 1 11794407 missense variant T/G snv 306
rs1799983
NOS3
0.430 0.880 7 150999023 missense variant T/A;G snv 0.75 246
rs1799945
LOC108783645 ; HFE
0.452 0.760 6 26090951 missense variant C/G;T snv 0.11 0.10 226
rs699
AGT
0.501 0.800 1 230710048 missense variant A/G snv 0.55 0.58 134
rs1801282
PPARG
0.500 0.840 3 12351626 missense variant C/G snv 0.11 8.9E-02 131
rs1805192
PPARG
0.510 0.840 3 12379739 missense variant C/G snv 121
rs5443
CDCA3 ; GNB3
0.532 0.760 12 6845711 synonymous variant C/T snv 0.36 0.44 106
rs1267969615
ACE
0.532 0.760 17 63490960 missense variant T/C snv 4.0E-06 100
rs6280
DRD3
0.602 0.520 3 114171968 missense variant C/T snv 0.63 0.54 57
rs2070744
NOS3
0.608 0.680 7 150992991 intron variant C/T snv 0.70 54
rs5186
AGTR1
0.630 0.560 3 148742201 3 prime UTR variant A/C snv 0.23 0.21 38
rs4762
AGT
0.637 0.440 1 230710231 missense variant G/A snv 0.12 0.11 35
rs8192678
PPARGC1A
0.667 0.440 4 23814039 missense variant C/T snv 0.31 0.26 28
rs660339
UCP2
0.695 0.320 11 73978059 missense variant G/A snv 0.41 0.43 24
rs2295490
TRIB3
0.724 0.320 20 388261 missense variant A/G;T snv 0.18; 4.0E-06 16
rs688
LDLR
0.742 0.400 19 11116926 synonymous variant C/T snv 0.39 0.34 16
rs713041
GPX4
0.776 0.400 19 1106616 stop gained T/A;C snv 4.2E-06; 0.58 16
rs751141
EPHX2
0.732 0.400 8 27516348 missense variant G/A snv 0.12 0.10 16
rs11643718
SLC12A3
0.807 0.240 16 56899607 missense variant G/A snv 0.11 8.4E-02 10
rs3918188
NOS3
0.776 0.280 7 151005693 intron variant C/A;T snv 10
rs316019
SLC22A2
0.790 0.360 6 160249250 missense variant A/C snv 0.90 0.89 8
rs2059806
INSR
0.807 0.240 19 7166365 synonymous variant C/G;T snv 4.0E-06; 0.26 7