Disease: Brain atrophy
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs6265
BDNF ; BDNF-AS
0.436 0.760 11 27658369 missense variant C/T snv 0.19 0.15 272
rs759834365
BDNF-AS ; BDNF
0.448 0.760 11 27658456 missense variant C/T snv 1.2E-05 237
rs63750231
PSEN1
0.689 0.160 14 73198100 missense variant A/C;G snv 23
rs1990622 0.742 0.200 7 12244161 downstream gene variant A/G snv 0.52 16
rs12273363
BDNF
0.807 0.120 11 27723312 intron variant T/C snv 0.16 11
rs363050
SNAP25-AS1 ; SNAP25
0.790 0.240 20 10253609 intron variant G/A snv 0.57 8
rs2298813
SORL1
0.790 0.120 11 121522975 missense variant G/A;T snv 7.2E-02; 4.0E-06 7
rs908867 0.851 0.160 11 27724217 intron variant C/G;T snv 7
rs704180
ABCC9
0.807 0.240 12 21841177 intron variant A/G snv 0.55 6
rs7127507
BDNF-AS ; BDNF
0.827 0.080 11 27693337 intron variant T/C snv 0.34 6
rs73069071
IAPP ; SLCO1A2
0.807 0.240 12 21357370 intron variant T/C snv 0.14 6
rs7354779
DNMT3L ; DNMT3L-AS1
0.827 0.200 21 44250887 missense variant T/C snv 0.21 6
rs730882147
MED20
0.851 0.080 6 41909351 missense variant C/G snv 7.0E-06 5
rs895293055
MED20
0.851 0.080 6 41909351 frameshift variant C/- delins 5
rs10761482
ANK3
0.851 0.120 10 60325579 intron variant T/C snv 0.70 4
rs1193124736
APP
0.851 0.120 21 25982462 missense variant G/T snv 7.0E-06 4
rs1133174
SORL1
0.882 0.120 11 121631046 3 prime UTR variant G/A snv 0.55 3
rs796052019
PCCA
0.882 0.160 13 100157297 missense variant G/A;T snv 4.0E-06 3
rs9637454
KCNMB2 ; KCNMB2-AS1
0.882 0.120 3 178539774 intron variant G/A snv 0.23 3
rs4935774
LOC105369536 ; SORL1
0.925 0.080 11 121451045 intron variant T/C snv 0.32 2