Disease: Exudative age-related macular degeneration
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs4880
SOD2
0.500 0.840 6 159692840 missense variant A/G snv 0.48 0.47 131
rs1061170
CFH
0.561 0.720 1 196690107 missense variant C/T snv 0.68 0.64 72
rs4073
CXCL8
0.566 0.800 4 73740307 upstream gene variant A/T snv 0.46 64
rs699947
VEGFA
0.570 0.680 6 43768652 upstream gene variant A/C;T snv 67
rs429358
APOE
0.590 0.600 19 44908684 missense variant T/C snv 0.14 0.16 66
rs833061
VEGFA
0.605 0.600 6 43769749 upstream gene variant C/G;T snv 42
rs800292
CFH
0.645 0.560 1 196673103 missense variant G/A snv 0.32 0.40 33
rs2075650
TOMM40
0.662 0.360 19 44892362 intron variant A/G snv 0.13 0.13 45
rs2071559
KDR
0.667 0.680 4 55126199 upstream gene variant A/G snv 0.53 26
rs1065489
CFH
0.695 0.440 1 196740644 missense variant G/T snv 0.20 0.15 19
rs10490924
ARMS2 ; LOC105378525
0.716 0.240 10 122454932 missense variant G/T snv 0.26 0.23 16
rs121913059
CFH
0.716 0.280 1 196747245 missense variant C/T snv 1.4E-04 1.9E-04 16
rs11200638
LOC105378525 ; HTRA1
0.724 0.280 10 122461028 non coding transcript exon variant G/A snv 0.23 14
rs2303790
CETP
0.724 0.280 16 56983380 missense variant A/G snv 2.6E-03 6.5E-04 19
rs3764261 0.732 0.280 16 56959412 upstream gene variant C/A snv 0.31 26
rs2146323
VEGFA
0.752 0.480 6 43777358 non coding transcript exon variant C/A snv 0.31 13
rs2230199
C3
0.763 0.240 19 6718376 missense variant G/C;T snv 0.15 10
rs9332739
CYP21A2 ; C2-AS1 ; C2
0.763 0.360 6 31936027 missense variant G/A;C snv 4.1E-06; 3.9E-02 10
rs2274700
CFH
0.776 0.240 1 196713817 synonymous variant G/A;C;T snv 0.44 11
rs57137919
ABCG1 ; LOC105372814
0.776 0.160 21 42218908 intron variant G/A snv 0.14 9
rs1136287
SERPINF1
0.790 0.280 17 1769982 missense variant C/T snv 0.61 0.69 8
rs641153
CFB ; CYP21A2
0.790 0.160 6 31946403 missense variant G/A;T snv 9.6E-02; 4.1E-06 7
rs10033900
CFI
0.807 0.040 4 109737911 intron variant T/C snv 0.54 7
rs141853578
CFI
0.807 0.040 4 109764664 missense variant C/T snv 4.2E-04 3.9E-04 6
rs1883025
ABCA1
0.807 0.120 9 104902020 intron variant C/T snv 0.28 13