Disease: Presenile dementia
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs34637584
LRRK2
0.583 0.480 12 40340400 missense variant G/A snv 5.3E-04 3.6E-04 78
rs104893877
SNCA
0.614 0.360 4 89828149 missense variant C/T snv 59
rs63751273
MAPT
0.645 0.280 17 46010389 missense variant C/T snv 42
rs76763715
GBA
0.658 0.520 1 155235843 missense variant T/C;G snv 2.3E-03 35
rs63750424
MAPT
0.677 0.240 17 46024061 missense variant C/T snv 1.6E-05 30
rs33939927
LRRK2
0.708 0.120 12 40310434 missense variant C/A;G;T snv 4.0E-06; 1.2E-05 24
rs63750756
MAPT
0.716 0.200 17 46010324 missense variant T/G snv 2.6E-05 23
rs1289324472
GBA
0.716 0.400 1 155236354 missense variant T/C snv 1.4E-05 21
rs2230288
GBA
0.776 0.160 1 155236376 missense variant C/T snv 1.0E-02 1.0E-02 18
rs63751438
MAPT
0.776 0.120 17 46010388 missense variant C/T snv 16
rs367543041
TARDBP
0.742 0.200 1 11022553 missense variant G/A;C snv 3.0E-05 15
rs104893875
SNCA
0.742 0.120 4 89828170 missense variant C/T snv 4.0E-06 13
rs242557
MAPT
0.752 0.200 17 45942346 intron variant G/A snv 0.36 12
rs767543900
MAPT
0.790 0.120 17 45971879 missense variant A/C;G snv 4.0E-06 10
rs63750802
PSEN1
0.851 0.080 14 73219144 missense variant T/G snv 7
rs63751032
PSEN1
0.851 0.080 14 73219156 missense variant T/A;G snv 7
rs201106962
SNCA
0.851 0.080 4 89828156 missense variant A/C snv 8.0E-05 7.0E-05 5
rs63750444
PSEN1
0.882 0.080 14 73192745 missense variant G/A snv 4