Disease: Impaired cognition
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs1799945
LOC108783645 ; HFE
0.452 0.760 6 26090951 missense variant C/G;T snv 0.11 0.10 226
rs63750215
PSEN2
0.701 0.240 1 226885603 missense variant A/T snv 19
rs781049584
APP
0.724 0.280 21 26021917 missense variant T/G snv 8.2E-06 7.0E-06 18
rs63750306
PSEN1
0.701 0.320 14 73173663 missense variant A/C;G;T snv 17
rs17125721
PSEN1
0.763 0.120 14 73206470 missense variant A/G snv 1.5E-02 1.5E-02 14
rs63750082
PSEN1
0.732 0.120 14 73192712 missense variant G/C;T snv 8.0E-06 13
rs1231783932
APP
0.763 0.120 21 26051171 missense variant T/A;C snv 1.2E-05 11
rs572842823
APP
0.763 0.160 21 25897626 missense variant T/A;G snv 11
rs28936379
PSEN2
0.807 0.120 1 226888977 missense variant A/C;G;T snv 4.0E-06 10
rs371425292
APP
0.763 0.160 21 25897627 missense variant C/A;T snv 8.0E-06 10
rs1223904774
APP
0.790 0.120 21 25891772 missense variant C/T snv 4.0E-06 7.0E-06 8
rs63750522
PSEN1
0.827 0.120 14 73173644 missense variant G/A;C snv 8
rs63750847
APP
0.790 0.120 21 25897620 missense variant C/T snv 4.5E-04 3.0E-04 8
rs10524523
TOMM40
0.807 0.200 19 44899792 intron variant TTTTTTTTTTTTTTTTTTTTTTT/-;T;TT;TTT;TTTT;TTTTT;TTTTTT;TTTTTTT;TTTTTTTT;TTTTTTTTT;TTTTTTTTTT;TTTTTTTTTTT;TTTTTTTTTTTT;TTTTTTTTTTTTT;TTTTTTTTTTTTTT;TTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT delins 7
rs63749806
PSEN1
0.827 0.080 14 73186902 missense variant T/C snv 7
rs1396086494
APP
0.851 0.080 21 26051069 missense variant G/A snv 4.0E-06 6
rs193922916
APP
0.827 0.080 21 25897619 missense variant G/A;C snv 6