Disease: Frontotemporal Lobar Degeneration
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs63751273
MAPT
0.645 0.280 17 46010389 missense variant C/T snv 42
rs63750424
MAPT
0.677 0.240 17 46024061 missense variant C/T snv 1.6E-05 30
rs75932628
LOC105375056 ; TREM2
0.662 0.480 6 41161514 missense variant C/A;T snv 6.8E-05; 2.6E-03 28
rs63750756
MAPT
0.716 0.200 17 46010324 missense variant T/G snv 2.6E-05 23
rs143624519
MAPT
0.724 0.240 17 45991484 missense variant G/A;T snv 1.5E-03; 1.2E-05 17
rs5848
FAM171A2 ; GRN
0.708 0.120 17 44352876 3 prime UTR variant C/T snv 0.41 17
rs1990622 0.742 0.200 7 12244161 downstream gene variant A/G snv 0.52 16
rs3173615
TMEM106B
0.807 0.200 7 12229791 missense variant C/A;G snv 0.49 12
rs80356726
TARDBP
0.763 0.120 1 11022352 splice acceptor variant G/A snv 4.0E-06 12
rs121909335
VCP
0.776 0.200 9 35065351 missense variant C/T snv 8.0E-06 9
rs63751294
GRN
0.827 0.120 17 44352404 stop gained C/T snv 8.0E-06 6
rs2234253
TREM2 ; LOC105375056
0.827 0.120 6 41161367 missense variant G/A;C;T snv 1.9E-04; 1.0E-02 5
rs63750349
MAPT
0.851 0.200 17 45996638 missense variant C/G;T snv 4.0E-06 5
rs63750129
MAPT
0.882 0.120 17 45996612 missense variant A/C snv 4.0E-06 4
rs63750541
GRN
0.851 0.160 17 44351586 missense variant G/A;C snv 8.4E-04 4
rs747019990
PRNP
0.851 0.120 20 4699336 missense variant C/T snv 3.6E-05 7.0E-06 4
rs753070659
GRN
0.851 0.160 17 44350481 missense variant G/A;C snv 1.2E-05 4
rs63750092
MAPT
0.882 0.120 17 46014277 missense variant A/T snv 3