Disease: Alzheimer's Disease
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs1217691063
MTHFR
0.330 0.920 1 11796309 missense variant A/G snv 4.0E-06 7.0E-06 614
rs397507444
MTHFR
0.405 0.880 1 11794407 missense variant T/G snv 306
rs4680
COMT ; MIR4761
0.442 0.920 22 19963748 missense variant G/A snv 0.46 0.44 249
rs1045642
ABCB1
0.456 0.840 7 87509329 synonymous variant A/G;T snv 0.50 214
rs1801133
MTHFR
0.472 0.880 1 11796321 missense variant G/A snv 0.31 0.27 174
rs1801131
MTHFR
0.535 0.840 1 11794419 missense variant T/G snv 0.29 0.26 93
rs6313
HTR2A
0.562 0.640 13 46895805 synonymous variant G/A snv 0.41 0.40 82
rs34637584
LRRK2
0.583 0.480 12 40340400 missense variant G/A snv 5.3E-04 3.6E-04 78
rs25531
SLC6A4 ; LOC105371720
0.581 0.520 17 30237328 upstream gene variant T/C snv 0.18 72
rs104893877
SNCA
0.614 0.360 4 89828149 missense variant C/T snv 59
rs121912438
SOD1
0.605 0.520 21 31667299 missense variant G/A;C;T snv 1.2E-05; 8.0E-06 58
rs2236225
MTHFD1
0.614 0.640 14 64442127 missense variant G/A snv 0.44 0.38 52
rs1051266
SLC19A1
0.627 0.640 21 45537880 missense variant T/C;G snv 0.55; 4.4E-06 41
rs4291
ACE
0.724 0.400 17 63476833 upstream gene variant T/A;C snv 20
rs63750215
PSEN2
0.701 0.240 1 226885603 missense variant A/T snv 19
rs63751438
MAPT
0.776 0.120 17 46010388 missense variant C/T snv 16
rs75634836
HTR2A
0.807 0.160 13 46835532 missense variant C/A;T snv 4.0E-06 11
rs28363170
SLC6A3
0.827 0.120 5 1393745 3 prime UTR variant -/AGTGGGGGCCCTGCATGCGTCCTGGGGTAGTACACGCTCC delins 8.1E-06 7
rs363043
SNAP25-AS1 ; SNAP25
0.925 0.080 20 10245498 intron variant C/T snv 0.30 3