Disease: Thyroid associated opthalmopathies
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs231775
CTLA4
0.504 0.720 2 203867991 missense variant A/G;T snv 0.42; 4.0E-06 115
rs5498
ICAM4 ; ICAM1
0.531 0.760 19 10285007 missense variant A/G snv 0.44 0.37 99
rs1799969
ICAM1
0.637 0.560 19 10284116 missense variant G/A snv 0.11 9.3E-02 38
rs225014
DIO2
0.695 0.400 14 80203237 missense variant T/C snv 0.41 0.39 22
rs1179251
IL22 ; LOC105369818
0.763 0.320 12 68251271 intron variant C/G snv 0.18 14
rs7530511
IL23R ; C1orf141
0.742 0.400 1 67219704 missense variant T/A;C snv 0.88 12
rs17879469
HLA-DRB1
0.763 0.360 6 32584333 missense variant C/G snv 1.3E-05 9
rs10004195
TLR10
0.790 0.320 4 38783103 upstream gene variant T/A snv 0.29 8
rs11675434
TPO
0.827 0.240 2 1404043 non coding transcript exon variant C/T snv 0.39 5
rs179247
TSHR
0.882 0.160 14 80966202 intron variant A/G snv 0.40 5
rs1061501
IRF7
0.851 0.200 11 614864 synonymous variant C/T snv 0.83 0.85 4
rs11611206
LOC105369818 ; MDM1
0.851 0.200 12 68274666 intron variant G/A snv 0.15 4