Disease: Impaired cognition
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs1217691063
MTHFR
0.330 0.920 1 11796309 missense variant A/G snv 4.0E-06 7.0E-06 614
rs6265
BDNF ; BDNF-AS
0.436 0.760 11 27658369 missense variant C/T snv 0.19 0.15 272
rs4680
COMT ; MIR4761
0.442 0.920 22 19963748 missense variant G/A snv 0.46 0.44 249
rs1799983
NOS3
0.430 0.880 7 150999023 missense variant T/A;G snv 0.75 246
rs759834365
BDNF-AS ; BDNF
0.448 0.760 11 27658456 missense variant C/T snv 1.2E-05 237
rs1801133
MTHFR
0.472 0.880 1 11796321 missense variant G/A snv 0.31 0.27 174
rs1805087
MTR
0.496 0.800 1 236885200 missense variant A/G snv 0.20 0.21 135
rs9939609
FTO
0.559 0.720 16 53786615 intron variant T/A snv 0.41 98
rs1061170
CFH
0.561 0.720 1 196690107 missense variant C/T snv 0.68 0.64 72
rs9340799
ESR1
0.583 0.680 6 151842246 intron variant A/G snv 0.32 62
rs1800497
ANKK1
0.620 0.400 11 113400106 missense variant G/A snv 0.26 0.26 56
rs2075650
TOMM40
0.662 0.360 19 44892362 intron variant A/G snv 0.13 0.13 45
rs53576
OXTR ; CAV3
0.641 0.320 3 8762685 intron variant A/G;T snv 42
rs6295
HTR1A
0.645 0.200 5 63962738 intron variant C/G snv 0.49 40
rs746682028
BDNF ; BDNF-AS
0.645 0.480 11 27658414 missense variant C/A;T snv 4.0E-06; 4.0E-06 36
rs1006737
CACNA1C
0.695 0.120 12 2236129 intron variant G/A snv 0.36 27
rs165599
ARVCF ; COMT
0.677 0.280 22 19969258 3 prime UTR variant G/A snv 0.56 27
rs4818
COMT ; MIR4761
0.683 0.440 22 19963684 synonymous variant C/G;T snv 0.34 27
rs1344706
ZNF804A
0.701 0.160 2 184913701 intron variant A/C;T snv 21
rs4291
ACE
0.724 0.400 17 63476833 upstream gene variant T/A;C snv 20
rs5522
NR3C2
0.732 0.320 4 148436323 missense variant C/T snv 0.88 0.89 19
rs1805054
HTR6
0.708 0.200 1 19666020 synonymous variant C/T snv 0.15; 8.0E-06 0.16 17
rs1625579
MIR137HG
0.763 0.160 1 98037378 intron variant G/T snv 0.78 14
rs2072446
LOC100288866 ; MIR6165 ; NGFR
0.776 0.160 17 49510457 missense variant C/T snv 5.2E-02 4.1E-02 11
rs10748842
NRG3
0.807 0.120 10 81889983 intron variant T/C snv 0.13 8