Disease: Impaired cognition
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs1217691063
MTHFR
0.330 0.920 1 11796309 missense variant A/G snv 4.0E-06 7.0E-06 614
rs6265
BDNF ; BDNF-AS
0.436 0.760 11 27658369 missense variant C/T snv 0.19 0.15 272
rs4680
COMT ; MIR4761
0.442 0.920 22 19963748 missense variant G/A snv 0.46 0.44 249
rs759834365
BDNF-AS ; BDNF
0.448 0.760 11 27658456 missense variant C/T snv 1.2E-05 237
rs1805087
MTR
0.496 0.800 1 236885200 missense variant A/G snv 0.20 0.21 135
rs34637584
LRRK2
0.583 0.480 12 40340400 missense variant G/A snv 5.3E-04 3.6E-04 78
rs2075650
TOMM40
0.662 0.360 19 44892362 intron variant A/G snv 0.13 0.13 45
rs75932628
LOC105375056 ; TREM2
0.662 0.480 6 41161514 missense variant C/A;T snv 6.8E-05; 2.6E-03 28
rs33939927
LRRK2
0.708 0.120 12 40310434 missense variant C/A;G;T snv 4.0E-06; 1.2E-05 24
rs375752214
NOS3
0.708 0.400 7 150998541 missense variant C/T snv 4.1E-06 4.2E-05 22
rs11136000
CLU
0.752 0.160 8 27607002 intron variant T/C snv 0.56 19
rs2230288
GBA
0.776 0.160 1 155236376 missense variant C/T snv 1.0E-02 1.0E-02 18
rs3851179 0.752 0.280 11 86157598 downstream gene variant T/C snv 0.70 15
rs3764650
ABCA7
0.790 0.200 19 1046521 intron variant T/G snv 0.14 9
rs363050
SNAP25-AS1 ; SNAP25
0.790 0.240 20 10253609 intron variant G/A snv 0.57 8
rs11637611
PARP6
0.851 0.160 15 72259371 intron variant C/T snv 0.63 4
rs11887120
DNMT3A
0.882 0.080 2 25262866 intron variant C/T snv 0.45 4
rs12752888
LINC02784
0.851 0.160 1 54527266 downstream gene variant T/C snv 0.26 4
rs16947151
ABI3
0.882 0.080 17 49213276 intron variant A/G snv 0.12 4
rs2070045
SORL1
0.851 0.080 11 121577381 synonymous variant T/G snv 0.32 0.23 4
rs541458 0.851 0.080 11 86077309 regulatory region variant C/T snv 0.71 4
rs5978930
ANOS1
0.882 0.080 X 8642266 intron variant T/C;G snv 4
rs7840202
UBR5
0.851 0.160 8 102296172 intron variant A/C snv 0.21 4
rs1187120 0.925 0.040 6 34182850 intergenic variant T/C snv 0.99 3