Disease: Alzheimer Disease, Late Onset
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs1217691063
MTHFR
0.330 0.920 1 11796309 missense variant A/G snv 4.0E-06 7.0E-06 614
rs397507444
MTHFR
0.405 0.880 1 11794407 missense variant T/G snv 306
rs6265
BDNF ; BDNF-AS
0.436 0.760 11 27658369 missense variant C/T snv 0.19 0.15 272
rs4680
COMT ; MIR4761
0.442 0.920 22 19963748 missense variant G/A snv 0.46 0.44 249
rs759834365
BDNF-AS ; BDNF
0.448 0.760 11 27658456 missense variant C/T snv 1.2E-05 237
rs34637584
LRRK2
0.583 0.480 12 40340400 missense variant G/A snv 5.3E-04 3.6E-04 78
rs1799864
CCR2
0.572 0.680 3 46357717 missense variant G/A snv 0.13 0.12 68
rs2075650
TOMM40
0.662 0.360 19 44892362 intron variant A/G snv 0.13 0.13 45
rs75932628
LOC105375056 ; TREM2
0.662 0.480 6 41161514 missense variant C/A;T snv 6.8E-05; 2.6E-03 28
rs11136000
CLU
0.752 0.160 8 27607002 intron variant T/C snv 0.56 19
rs3851179 0.752 0.280 11 86157598 downstream gene variant T/C snv 0.70 15
rs972936
IGF1 ; LINC02456
0.807 0.200 12 102431143 intron variant T/C snv 0.70 12
rs3764650
ABCA7
0.790 0.200 19 1046521 intron variant T/G snv 0.14 9
rs754203
CYP46A1
0.807 0.200 14 99691630 non coding transcript exon variant A/G snv 0.27 6
rs610932
MS4A6A
0.851 0.080 11 60171834 downstream gene variant T/G snv 0.57 5
rs11767557
EPHA1-AS1
0.882 0.080 7 143412046 intron variant T/C snv 0.18 4
rs12344615
UBQLN1
0.851 0.080 9 83666280 intron variant A/C;G snv 4
rs2070045
SORL1
0.851 0.080 11 121577381 synonymous variant T/G snv 0.32 0.23 4
rs541458 0.851 0.080 11 86077309 regulatory region variant C/T snv 0.71 4
rs1784933
SORL1
0.882 0.080 11 121618707 intron variant G/A snv 0.84 3
rs3747742
TREML2
0.882 0.080 6 41194780 missense variant T/C snv 0.33 0.29 3
rs641120
SORL1
0.882 0.080 11 121510256 intron variant G/A snv 0.38 3
rs11218304
LOC105369535 ; SORL1
0.925 0.080 11 121478402 intron variant A/G snv 0.30 2
rs9340803
ESR1
0.925 0.080 6 151842832 intron variant A/G snv 1.0E-03 3.8E-04 2