Disease: Major Depressive Disorder
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs1217691063
MTHFR
0.330 0.920 1 11796309 missense variant A/G snv 4.0E-06 7.0E-06 614
rs397507444
MTHFR
0.405 0.880 1 11794407 missense variant T/G snv 306
rs6265
BDNF ; BDNF-AS
0.436 0.760 11 27658369 missense variant C/T snv 0.19 0.15 272
rs4680
COMT ; MIR4761
0.442 0.920 22 19963748 missense variant G/A snv 0.46 0.44 249
rs759834365
BDNF-AS ; BDNF
0.448 0.760 11 27658456 missense variant C/T snv 1.2E-05 237
rs1801133
MTHFR
0.472 0.880 1 11796321 missense variant G/A snv 0.31 0.27 174
rs662
PON1
0.485 0.840 7 95308134 missense variant T/C snv 0.38 0.42 157
rs1805087
MTR
0.496 0.800 1 236885200 missense variant A/G snv 0.20 0.21 135
rs2228570
VDR
0.521 0.760 12 47879112 start lost A/C;G;T snv 0.63 99
rs25531
SLC6A4 ; LOC105371720
0.581 0.520 17 30237328 upstream gene variant T/C snv 0.18 72
rs1800497
ANKK1
0.620 0.400 11 113400106 missense variant G/A snv 0.26 0.26 56
rs53576
OXTR ; CAV3
0.641 0.320 3 8762685 intron variant A/G;T snv 42
rs6311
HTR2A
0.645 0.640 13 46897343 upstream gene variant C/T snv 0.40 41
rs4818
COMT ; MIR4761
0.683 0.440 22 19963684 synonymous variant C/G;T snv 0.34 27
rs6314
HTR2A
0.677 0.360 13 46834899 missense variant G/A snv 7.9E-02 9.5E-02 23
rs6994992
NRG1
0.790 0.120 8 31638065 upstream gene variant C/A;T snv 13
rs2710102
CNTNAP2
0.790 0.120 7 147877298 intron variant A/G;T snv 12
rs3746544
SNAP25 ; SNAP25-AS1
0.790 0.120 20 10306436 3 prime UTR variant G/T snv 0.68 10
rs779867
GRM7
0.776 0.120 3 7442784 intron variant T/C;G snv 9
rs1390938
SLC18A1
0.807 0.200 8 20179202 missense variant A/G snv 0.71 0.78 7
rs6323
MAOA
0.807 0.040 X 43731789 synonymous variant G/T snv 0.65 7
rs6782011
GRM7
0.807 0.120 3 7457960 intron variant C/T snv 0.52 7